Protein Alignment Tgfb2 and scw

DIOPT Version :9

• Sequence 1: NP_001316036.1
• Gene: Tgfb2 / 21808
• MGIID: 98726
• Length: 442
• Species: Mus musculus
• Sequence 2: NP_001286088.1
• Gene: scw / 46000
• FlyBaseID: FBgn0005590
• Length: 400
• Species: Drosophila melanogaster
• Alignment Length: 469
• Identity: 102/469 - (21%)
• Similarity: 185/469 - (39%)
• Gaps: 102/469 - (21%)

Mouse     5 VLSTFLLLHLVPVALS---LSTCSTLDMDQFMRKRIEAIRGQILSKLKLTSPPEDYPEPDEVPPE 66
            :|:.|.|..|...|.:   ::|.:.::|..: :||..:.:.:::..|.|...|....||
  Fly     1 MLNVFFLTSLFYAASATTYVTTNNHIEMPIY-QKRPLSEQMEMIDILDLGDRPRRQAEP------ 58

Mouse    67 VISIYNSTRDLLQEKASRRAAACERERSDEEYYAKEVYKIDMPSHLPSETVCPVVTTPSGSLGSF 131
              :::||....|.|..:.   ..|.:...|..:.:....:|....:.:|....:.:  ..|:.:|
  Fly    59 --NLHNSASKFLLEVYNE---ISEDQEPKEVLHQRHKRSLDDDILISNEDRQEIAS--CNSILTF 116

Mouse   132 CSR-QSQVLCGYLDAIPPTFYRPYFRIVRFDVSTMEKNASNLVKAEFRVFRLQNPKARVAEQRIE 195
            .|| :.:.|...||           ..:.|:.:.:..:.| ||:|..|:::..:...|.|...:.
  Fly   117 SSRLKPEQLDNELD-----------MHITFNTNDVPVDLS-LVQAMLRIYKQPSLVDRRANFTVS 169

Mouse   196 LYQILKSKDLTSPTQRYIDSKVVKTRAEGEWLSFDVTDAVQEWLHHK--DRNLGFKISLHCPCCT 258
            :|:.|.::...|  .|.:.| |..|.::..||.|::||.::.|||:|  .|....:||:
  Fly   170 VYRKLDNRQDFS--YRILGS-VNTTSSQRGWLEFNLTDTLRYWLHNKGLQRRNELRISI------ 225

Mouse   259 FVPSNNYIIPNKSEELEARFAGIDGTSTYASGDQKTIKSTRKKTSGKT--------PHLLLMLLP 315
                                 |....||:|:|   .:.....:||.:.        |.||:
  Fly   226 ---------------------GDSQLSTFAAG---LVTPQASRTSLEPFIVGYFNGPELLV---- 262

Mouse   316 SYRLESQQSSR--RKKRA------------LDAAYCFRNVQDNCCLRPLYIDFKRDLGWKWIHEP 366
              :::..:..|  .|:||            :|   .:|..| :|......:|||......|:..|
  Fly   263 --KIQKLRFKRDLEKRRAGGGSPPPPPPPPVD---LYRPPQ-SCERLNFTVDFKELHMHNWVIAP 321

Mouse   367 KGYNANFCAGACPYLWSSD---TQHTKVLSLYNTINPEASASPCCVSQDLEPLTILYYIG-NTPK 427
            |.:.|.||.|.|.:...:.   |.|..|.:|.:...|.. ..||||...|..:|||.|:. :...
  Fly   322 KKFEAYFCGGGCNFPLGTKMNATNHAIVQTLMHLKQPHL-PKPCCVPTVLGAITILRYLNEDIID 385

Mouse   428 IEQLSNMIVKSCKC 441
            :.:....:.|.|.|
  Fly   386 LTKYQKAVAKECGC 399

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tgfb2	NP_001316036.1	TGFb_propeptide	21..256	CDD:279078	51/237 (22%)
		TGF_beta	344..441	CDD:278448	28/100 (28%)
scw	NP_001286088.1	TGFb_propeptide	39..254	CDD:279078	54/272 (20%)
		TGFB	300..400	CDD:214556	29/101 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810