Protein Alignment ALDH3A1 and Aldh-III

DIOPT Version :10

• Sequence 1: XP_047291551.1
• Gene: ALDH3A1 / 218
• HGNCID: 405
• Length: 570
• Species: Homo sapiens
• Sequence 2: NP_724562.2
• Gene: Aldh-III / 45398
• FlyBaseID: FBgn0010548
• Length: 564
• Species: Drosophila melanogaster
• Alignment Length: 321
• Identity: 176/321 - (54%)
• Similarity: 236/321 - (73%)
• Gaps: 2/321 - (0%)

Human   244 SVCSAGNSVVLKPSELSENMASLLATIIPQYLDKDLYPVINGGVPETTELLKERFDHILYTGSTG 308
            |..:|||.||:||||::.|.|..:|.:||:|||.|.|||:.||..||.|||.:|||:|.|||||.
  Fly   193 SAIAAGNCVVIKPSEIAANCAKFIADVIPKYLDNDCYPVVCGGPSETAELLNQRFDYIFYTGSTR 257

Human   309 VGKIIMTAAAKHLTPVTLELGGKSPCYVDKNCDLDVACRRIAWGKFMNSGQTCVAPDYILCDPSI 373
            |||||..||.|:|||.|||||||||||:||:.|:..|.:||.|||.:|.||||:|||||||...:
  Fly   258 VGKIIHAAANKYLTPTTLELGGKSPCYIDKSVDMRTAVKRILWGKLINCGQTCIAPDYILCSKEV 322

Human   374 QNQIVEKLKKSLKEFYGEDAKKSRDYGRIISARHFQRVMGLIEGQKVAYGGTGDAATRYIAPTIL 438
            |.:.:.:.|..|||:|||:.:.|.|..|:|:|.:|||::||::..:||.||..||:.|:|.||||
  Fly   323 QEKFIVEAKDVLKEWYGENIQSSPDLSRVINANNFQRLLGLMKSGRVAVGGNYDASERFIEPTIL 387

Human   439 TDVDPQSPVMQEEIFGPVLPIVCVRSLEEAIQFINQREKPLALYMFSSNDKVIKKMIAETSSGGV 503
            .||....|:|:||||||:|||..|.|..:||:|||.|||||.:|:||:::|::|:....|:|||.
  Fly   388 VDVKETDPIMEEEIFGPILPIFNVESAYDAIKFINAREKPLVIYVFSNSNKLVKEFRRSTTSGGF 452

Human   504 AANDVIVHITLHSLPFGGVGNSGMGSYHGKKSFETFSHRRSCLVRPL--MNDEGLKVRYPP 562
            ::|:.|:|..:..|||||||.||||.||||..||||:|::|||.:.|  :.::....||||
  Fly   453 SSNETIMHCGVDVLPFGGVGMSGMGRYHGKYGFETFTHKKSCLGKDLSPLGEKLSSARYPP 513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ALDH3A1	XP_047291551.1	ALDH-SF	<248..564	CDD:448367	175/317 (55%)
Aldh-III	NP_724562.2	ALDH_F3AB	72..515	CDD:143450	176/321 (55%)