Protein Alignment ALDH3A1 and Ssadh

DIOPT Version :10

• Sequence 1: XP_047291551.1
• Gene: ALDH3A1 / 218
• HGNCID: 405
• Length: 570
• Species: Homo sapiens
• Sequence 2: NP_651408.1
• Gene: Ssadh / 43092
• FlyBaseID: FBgn0039349
• Length: 509
• Species: Drosophila melanogaster
• Alignment Length: 318
• Identity: 99/318 - (31%)
• Similarity: 157/318 - (49%)
• Gaps: 39/318 - (12%)

Human   241 RPGSVCSAGNSVVLKPSELSENMASLLATIIPQYLDKDLYPVINGGVPE------TT-------E 292
            :.|:..:||.:||:||||.:...|..:|.:           .::.|:|:      ||       :
  Fly   187 KAGAALAAGCTVVVKPSEDTPLTALAVAKL-----------AVDAGIPKGVINVVTTNKAAPIGD 240

Human   293 LLKERFD--HILYTGSTGVGKIIMTAAAKHLTPVTLELGGKSPCYVDKNCDLDVACRRIAWGKFM 355
            |..:..|  .|.:||||.|||::...:|..:..:.|||||.:|..|..:.|::.|.......||.
  Fly   241 LFCKSPDVRGISFTGSTEVGKLLFRNSADGIKRICLELGGNAPFIVFDSADIEKAVDGAMASKFR 305

Human   356 NSGQTCVAPDYILCDPSIQNQIVEKLKKSLKEF-YGEDAKKSRDYGRIISARHFQRVMGLIEGQK 419
            |.|||||:.:......|:.::.|.:|||.::.. .|:........|.:|:...|.:|.|.:|..:
  Fly   306 NCGQTCVSANRFFVQDSVYDKFVGQLKKRVEALKIGDGQGCDVQIGPLINEMQFNKVSGFVEDAR 370

Human   420 -----VAYGG--TGDAATRYIAPTILTDVDPQSPVMQEEIFGPVLPIVCVRSLEEAIQFINQREK 477
                 :..||  ..|..:.:.||||:|||.|.:.:..||:||||:.|:..|..|||::..|...:
  Fly   371 SKKANIILGGQPLPDKGSLFYAPTIVTDVPPSAQLYSEEVFGPVVSIIRFRDEEEAVKKANDTRR 435

Human   478 PLALYMFSSNDKVIKKMIAETSSGGVAANDVIVHITLHSLPFGGVGNSGM---GSYHG 532
            .||.|.:|.|.:.:.::......|.|..|:.|  |:....|||||..||:   ||.||
  Fly   436 GLAGYFYSENLQQVFRVAKRLEVGMVGVNEGI--ISAAEAPFGGVKESGVGREGSKHG 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ALDH3A1	XP_047291551.1	ALDH-SF	<248..564	CDD:448367	98/311 (32%)
Ssadh	NP_651408.1	ALDH_F5_SSADH_GabD	49..503	CDD:143421	99/318 (31%)