Protein Alignment ALDH3A1 and CG2336

DIOPT Version :10

• Sequence 1: XP_047291551.1
• Gene: ALDH3A1 / 218
• HGNCID: 405
• Length: 570
• Species: Homo sapiens
• Sequence 2: NP_731094.3
• Gene: CG2336 / 40804
• FlyBaseID: FBgn0037455
• Length: 322
• Species: Drosophila melanogaster
• Alignment Length: 331
• Identity: 67/331 - (20%)
• Similarity: 133/331 - (40%)
• Gaps: 64/331 - (19%)

Human   233 PLVKYPGHRPGSVCSAGNSVVLKPSELSENMASLLATIIPQYLDKDLYPVINGGVPETTELLKER 297
            ||:.| |.....||:       ||.::|   ..|:..|..::..||..|.....||..:
  Fly    28 PLIDY-GFIYNLVCN-------KPRDVS---VPLILEIETEFKSKDSAPEKPKKVPRLS------ 75

Human   298 FDHILYTGSTGVGKIIMTAAAKHLTPVTLELGGKSPCYVDKNCDLDVACRRIAWGKFMNSGQTCV 362
                .::.|:.:.:      .:....|.::....||..:....|.|:.|......:.::....|.
  Fly    76 ----YHSRSSSMSE------DEPEPEVQVKYQWNSPRLMILCEDGDINCALHYLVESLHDPFACN 130

Human   363 APDYILCDPSIQNQIVEKLKKSLKEFYGEDAKKSRDY-GRIISARHFQRVMGLIEGQKVAYGGTG 426
            |...:....||..:.|::::..|:..       |.|. |..:.....:|: |.::.:::.  |..
  Fly   131 AVATLFLQESILEEFVDRIRDRLEPL-------STDISGHPVYIMTLERI-GHLQAKRIV--GNP 185

Human   427 DAATRYIAPTILTDVDPQSPVMQEEIFGP--VLPIVCVRSLEEAIQFINQREKPLALYMFSS--- 486
            .......:|.::.|:..:  .:.:   ||  |:.:...|:::||::.  |.::||   .|:|
  Fly   186 KTVPENASPMLVYDLSHR--YLAD---GPTGVITLHTFRTMKEAVEL--QAKEPL---NFTSVCI 240

Human   487 -NDKVIK--KMIAETSSGGVAANDVIVHITLHSLPFGGVGNSG--MGSYHGKKSFE--TFSHRRS 544
             |:|:..  :::|..|......|...|::...:|||....||.  :..||    :|  ||..:|.
  Fly   241 WNEKLAAAYELVARLSPLIFTINCYYVNLNEITLPFVCNFNSAKIIDGYH----YESLTFKGKRK 301

Human   545 CLVRPL 550
            .:|.|:
  Fly   302 VVVHPV 307

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ALDH3A1	XP_047291551.1	ALDH-SF	<248..564	CDD:448367	61/316 (19%)
CG2336	NP_731094.3	DUF1487	97..311	CDD:254173	49/235 (21%)