Protein Alignment ALDH3A1 and P5CDh1

DIOPT Version :10

• Sequence 1: XP_047291551.1
• Gene: ALDH3A1 / 218
• HGNCID: 405
• Length: 570
• Species: Homo sapiens
• Sequence 2: NP_649368.2
• Gene: P5CDh1 / 40434
• FlyBaseID: FBgn0037138
• Length: 574
• Species: Drosophila melanogaster
• Alignment Length: 350
• Identity: 90/350 - (25%)
• Similarity: 138/350 - (39%)
• Gaps: 54/350 - (15%)

Human   249 GNSVVLKPSELSENMASLLATIIPQYLDKDLYP--VIN-----GGVPETTELLKERFDHILYTGS 306
            ||.|:.|||:    .|.|...||.:.:.:...|  |:|     |.|...|.........|.:|||
  Fly   238 GNGVLWKPSD----TAMLSNWIIFKIMREAGVPDGVVNFVPADGPVFGDTITASPHLAGINFTGS 298

Human   307 TGVGKIIMTAAAKHL------TPVTLELGGKSPCYVDKNCDLDVACRRIAWGKFMNSGQTCVAPD 365
            ......:......::      ..:|.|.|||:..::..:.|::..........|...||.|.|..
  Fly   299 VPTFNRLWKQVGNNIDNYVNFPRLTGECGGKNFHFIHASADVESVVTSTIRSAFEYCGQKCSACS 363

Human   366 YILCDPSIQNQIVEKLK-KSLKEFYGEDAKKSRDYGRIISARHFQRVMGLIEGQK------VAYG 423
            .:....|:..||.|.|. ::.|...|:....|.....:|..:.|:|:.|.||..|      :..|
  Fly   364 RMYVPESLWPQIKEGLVCEAAKLKIGDVQDFSSFTSAVIDDKAFKRITGYIEHAKKSPNLEILAG 428

Human   424 GT-GDAATRYIAPTILTDVDPQSPVMQEEIFGPVLPIVCVR--SLEEAIQFINQREK-PLALYMF 484
            || .|:...::.|||:...||:..:|.||||||||.|...:  .|.|.::.::...| .|...:|
  Fly   429 GTYSDSKGYFVNPTIVLSKDPKDRIMTEEIFGPVLSIYVYKESDLLETMKLVHTSTKFALTGAVF 493

Human   485 SSNDKVIKKMIAE--TSSGGVAANDVIVHITLHSLPFGGVGNSGMGSYHGKKSF----------- 536
            ..::..:|..:.|  .::|....||......:...||||...||.....|...:
  Fly   494 GQDEDFVKCALQEFKMAAGNFYINDKSTGSVVGQQPFGGGRMSGTNDKAGGPHYILRWTSPQSIK 558

Human   537 ETFSHRRSCLVRPLMNDEGLKVRYP 561
            |||.        ||.:     |.||
  Fly   559 ETFV--------PLRD-----VNYP 570

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ALDH3A1	XP_047291551.1	ALDH-SF	<248..564	CDD:448367	89/349 (26%)
P5CDh1	NP_649368.2	ALDH_F4-17_P5CDH	41..563	CDD:143441	85/336 (25%)