Protein Alignment ALDH3A1 and CG6661

DIOPT Version :10

• Sequence 1: XP_047291551.1
• Gene: ALDH3A1 / 218
• HGNCID: 405
• Length: 570
• Species: Homo sapiens
• Sequence 2: NP_648686.3
• Gene: CG6661 / 39556
• FlyBaseID: FBgn0036403
• Length: 581
• Species: Drosophila melanogaster
• Alignment Length: 351
• Identity: 80/351 - (22%)
• Similarity: 145/351 - (41%)
• Gaps: 51/351 - (14%)

Human   244 SVCSA--GNSVVLKPSELSENMASLLATIIPQYLDKDLYPVINGGVPETTELLKERF-DHILYTG 305
            ::|.|  ||:|:..|   |..:|.:...|...:.:..|...:...||....|..:.. |.:.:.|
  Fly   241 ALCPALMGNTVLWNP---SLEVAPVSYLIFRAFQEAGLPSGVINFVPANERLFLDTITDAVHFAG 302

Human   306 ST---------GVGKIIMTAAAKHL--TPVTLELGGKSPCYVDKNCDLD---VACRRIAW---GK 353
            ..         .|.|::.....:::  ..:..|..|::..:|..:..::   .|..:.|:   |:
  Fly   303 LNTQASAAFYRHVHKLVSDRMERYICFPRLVAECPGQNFHFVHASAKVESVVSATVQAAFGFAGQ 367

Human   354 FMNSGQTCVAPDYILCDPSIQNQIVEKLKKSLKEFYGEDAKKSRDYGRIISARHFQRVMGLIEGQ 418
            :.||......|..:.  |.::.::||..::..   .|:..:...|.|.::....|:|:..|::..
  Fly   368 YANSLSRMYVPSSMW--PRLREELVEATEQLT---IGDPIESETDIGAMVHINDFRRMQKLLQRT 427

Human   419 K----VAYGGTGDAATRYIAPTILTDVDPQSPVMQEEIFGPVLPIVCVR--SLEEAIQF-INQRE 476
            |    :..|...|:..|::.|||:...||..|::.|...||.||:....  |..||::. .||..
  Fly   428 KNMEQLCGGSCDDSTGRFVDPTIVRVSDPLDPLLCEPCCGPFLPVFVYSDDSFSEALKLAANQSR 492

Human   477 KPLALYMFSSNDKVIKKMIAE--TSSGGVAANDVIVHITLHSLPFGGVGNSGMGSYHGKKSFETF 539
            ..|:..:|:|.|:||...:.:  .|:..:..|:.....|....||||...||.....|...|
  Fly   493 YALSGSIFASQDEVILHCLNQLRMSASNLYVNERCTGSTYGLTPFGGNRLSGTNDKSGSAYF--- 554

Human   540 SHRRSCLVR---PLMNDEGLKVRYPP 562
                  |:|   ||:.:|  .|..||
  Fly   555 ------LMRWSSPLLIEE--TVDGPP 572

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ALDH3A1	XP_047291551.1	ALDH-SF	<248..564	CDD:448367	79/347 (23%)
CG6661	NP_648686.3	ALDH-SF	68..567	CDD:448367	77/344 (22%)