Protein Alignment ALDH3A1 and CG8665

DIOPT Version :10

• Sequence 1: XP_047291551.1
• Gene: ALDH3A1 / 218
• HGNCID: 405
• Length: 570
• Species: Homo sapiens
• Sequence 2: NP_610107.1
• Gene: CG8665 / 35407
• FlyBaseID: FBgn0032945
• Length: 913
• Species: Drosophila melanogaster
• Alignment Length: 393
• Identity: 107/393 - (27%)
• Similarity: 174/393 - (44%)
• Gaps: 60/393 - (15%)

Human   174 ARWCS--SGQRVPVCVPLSCARACSWVCPVTCACLLTTLPSTVPRTHNGGEASGVVLGRAEPLVK 236
            |.||.  .|..:||    :.||                 |:.| .|....|..| |.|...|. .
  Fly   544 AGWCDKIQGNTIPV----NPAR-----------------PNNV-LTFTRKEPIG-VCGLITPW-N 584

Human   237 YP----GHRPGSVCSAGNSVVLKPSELSENMASLLATIIPQYLDKDLYP--VINGGVPETTELLK 295
            ||    ..:..:..:|||:.::||::    ...|.|....:...:..:|  |||....:.::..:
  Fly   585 YPLMMLSWKMAACIAAGNTCLIKPAQ----TCPLTALKFAELTVRAGFPPGVINVLPGKGSDAGQ 645

Human   296 ERFDHIL-----YTGSTGVGKIIMTAAA-KHLTPVTLELGGKSPCYVDKNCDLDVACRRIAWGKF 354
            ...||.|     :||||.:||.||.:.| .:|...:||||||||..:..:||:|.|.:......|
  Fly   646 AVADHELVRKLGFTGSTPIGKHIMKSCADSNLKKCSLELGGKSPLIIFADCDMDKAVKHGMSSVF 710

Human   355 MNSGQTCVAPDYILCDPSIQNQIVEKLKKSLKEF-YGEDAKKSRDYGRIISARHFQRVM-----G 413
            .|.|:.|:|...:..:..|.::.:.::.|.|:.. .|:...:|..:|......||.:::     |
  Fly   711 FNKGENCIAAGRLFVEDRIHDEFIRRVLKDLRTMTIGDPLDRSTAHGPQNHKAHFDKLLEFCRRG 775

Human   414 LIEGQKVAYGG--TGDAATRYIAPTILTDVDPQSPVMQEEIFGPVLPIVCVR--SLEEAIQFINQ 474
            :.||.|:.|||  ..:....:..||:.|:|.....:.|||.|||::.|....  .::..:|..|:
  Fly   776 VDEGAKLVYGGCRVPNLKGYFFTPTVFTNVTDDMFIAQEESFGPIMIISKFNGSDIDSLMQRANR 840

Human   475 REKPLALYMFSSNDKVIKKMIAETSSGGVAANDVIVHI---TLHSLPFGGVGNSGMGSYHGKKSF 536
            .|..||..:|:   |.|.|  |...:..:.|..|.|::   |..:.||||...||.|...|:::.
  Fly   841 TEYGLASGVFT---KDIGK--ALNFADRIEAGTVFVNVYNKTDVAAPFGGFKQSGYGKDLGQEAL 900

Human   537 ETF 539
            ..:
  Fly   901 NEY 903

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ALDH3A1	XP_047291551.1	ALDH-SF	<248..564	CDD:448367	89/313 (28%)
CG8665	NP_610107.1	FMT_core	5..207	CDD:444886
		FDH_Hydrolase_C	212..316	CDD:187731
		PP-binding	336..394	CDD:425746
		ALDH_F1L_FTFDH	428..913	CDD:143458	107/393 (27%)