Protein Alignment ALDH3A1 and Aldh

DIOPT Version :10

• Sequence 1: XP_047291551.1
• Gene: ALDH3A1 / 218
• HGNCID: 405
• Length: 570
• Species: Homo sapiens
• Sequence 2: NP_609285.1
• Gene: Aldh / 34256
• FlyBaseID: FBgn0012036
• Length: 520
• Species: Drosophila melanogaster
• Alignment Length: 364
• Identity: 104/364 - (28%)
• Similarity: 166/364 - (45%)
• Gaps: 54/364 - (14%)

Human   229 GRAEPL----VKYPGHRPGSVC---------------------SAGNSVVLKPSELSENMASLLA 268
            |:..|:    ..|..|.|..||                     :.||::||||:|    ..||.|
  Fly   161 GKTIPMDGDFFTYTRHEPVGVCGQIIPWNFPILMMAWKLGPALATGNTIVLKPAE----QTSLTA 221

Human   269 TIIPQYLDKDLYP--VIN--GGVPETTELLKER--FDHILYTGSTGVGKIIMTAAAK-HLTPVTL 326
            ..|.|.:.:..:|  |:|  .|.......|...  .|.:.:||||.|||:|..|:.. :|..|||
  Fly   222 LYIAQLVKEAGFPEGVVNVVPGFGTAGAALANHCDVDKVAFTGSTDVGKLIQLASGNTNLKRVTL 286

Human   327 ELGGKSPCYVDKNCDLDVACRRIAWGKFMNSGQTCVAPDYILCDPSIQNQIVEK-LKKSLKEFYG 390
            |||||||..:..:.|:|.|.....:|.|.|.||.|.|......:..|.::.||: .:::.|...|
  Fly   287 ELGGKSPNIILSDTDMDYAVETAHFGLFFNMGQCCCAGSRTFVEDKIYDEFVERSAERAKKRTVG 351

Human   391 EDAKKSRDYGRIISARHFQRVMGLI-----EGQKVAYGGTGDAAT--RYIAPTILTDVDPQSPVM 448
            .....:.:.|..::....::::|:|     :|.|:..||:.....  .::.||:..||.....:.
  Fly   352 NPFDLNTEQGPQVNEEQMEKILGMIKTGKKQGAKLVAGGSRPEGLPGYFVQPTVFADVQDDMTIA 416

Human   449 QEEIFGPVLPIVCVRSLEEAIQFINQREKPLALYMFSSN-DKVIKKMIAETSSGGVAANDVIV-- 510
            :|||||||..::..:.|:|.|:..|..|..||..:|:.: ||      |....||:.|..|.|
  Fly   417 REEIFGPVQQLIRFKKLDEVIERANNSEYGLAAAVFTKDLDK------ANYIVGGLRAGTVWVNT 475

Human   511 -HITLHSLPFGGVGNSGMGSYHGKKSFETFSHRRSCLVR 548
             ::.....||||...||.|..:|:.:...::..:|.:|:
  Fly   476 YNVLAAQAPFGGYKMSGHGRENGEYALSNYTEVKSVIVK 514

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ALDH3A1	XP_047291551.1	ALDH-SF	<248..564	CDD:448367	97/320 (30%)
Aldh	NP_609285.1	ALDH_F1AB_F2_RALDH1	34..514	CDD:143459	103/362 (28%)