Protein Alignment ALDH3A1 and P5CDh2

DIOPT Version :10

• Sequence 1: XP_047291551.1
• Gene: ALDH3A1 / 218
• HGNCID: 405
• Length: 570
• Species: Homo sapiens
• Sequence 2: NP_788705.1
• Gene: P5CDh2 / 32625
• FlyBaseID: FBgn0053092
• Length: 614
• Species: Drosophila melanogaster
• Alignment Length: 357
• Identity: 78/357 - (21%)
• Similarity: 146/357 - (40%)
• Gaps: 67/357 - (18%)

Human   249 GNSVVLKPSELSENMASLLATIIPQYLDKDLYPVI-NGGVP---------ETTELLKERFDH--- 300
            ||||:.|||:         :.|:..|.   ::..: ..|||         |.|........|
  Fly   246 GNSVIWKPSD---------SAILSNYF---VFKALREAGVPDGVVNFVPAEETTFASVVTQHPKL 298

Human   301 --ILYTGSTGVGKIIMTAAAKHLT------PVTLELGGKSPCYVDKNCDLDVACRRIAWGKFMNS 357
              |.:||::.|.|::....|:::.      .:..|.|||:..:|..:.:.:.|........|..:
  Fly   299 AGINFTGTSTVLKVLWQLVAQNINFYQNYPRLVGEGGGKNFHFVHSSAEPETAVACTIRAAFEYA 363

Human   358 GQTCVAPDYILCDPSI-QNQIVEKLKK-SLKEFYGEDAKKSRDY-GRIISARHFQRV---MGLIE 416
            ||.|.:...:....|: ||.|.|.|.: :......:||.....: ..:|:.|.:.|:   :..|:
  Fly   364 GQKCSSCSMLYVPESLWQNHIREPLLEITASLVVRQDATYCDSFCSAVINRRAYDRIYMWLRYID 428

Human   417 GQ---KVAYGGTGDAAT-RYIAPTILTDVDPQSPVMQEEIFGPVLPIVCV--RSLEEAIQFINQR 475
            ..   ::..||:.|... .|:.||::...|..:.:.:||:..|:|.:...  ..|:|.::.:.|.
  Fly   429 QSPSCQILVGGSCDKRRGYYVDPTVVLVKDLDNIICREELLAPILGVYVYPDHKLKETMEKVAQI 493

Human   476 EKPLALYMFSSNDKVIKKM--IAETSSGGVAANDVIVHITLHSLPFGGVGNSG----MGSYHG-- 532
            ...|...:|:.:...|::.  ....:.|.:..||....:.:...|||....:|    :|:.|.
  Fly   494 NHGLTGSVFAQDQNFIEEAYDAFRVNVGNLNVNDKSTGLMVGQQPFGAGHMTGTSDKLGTPHSLL 558

Human   533 --------KKSFETFSHRRSCLVRPLM--NDE 554
                    |:|::|  ||.  :..|.|  ||:
  Fly   559 RWTSPQVIKESYKT--HRN--IFYPYMQINDQ 586

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ALDH3A1	XP_047291551.1	ALDH-SF	<248..564	CDD:448367	78/357 (22%)
P5CDh2	NP_788705.1	ALDH-SF	50..570	CDD:448367	70/335 (21%)