Protein Alignment Morf4l1 and MRG15

DIOPT Version :10

• Sequence 1: NP_001034236.1
• Gene: Morf4l1 / 21761
• MGIID: 1096551
• Length: 362
• Species: Mus musculus
• Sequence 2: NP_001262588.1
• Gene: MRG15 / 41850
• FlyBaseID: FBgn0027378
• Length: 429
• Species: Drosophila melanogaster
• Alignment Length: 451
• Identity: 159/451 - (35%)
• Similarity: 220/451 - (48%)
• Gaps: 134/451 - (29%)

Mouse     6 DPKPKFQEGERVLCFHGPLLYEAKCVKVAIKDKQVKYFIHYSGWNKKSAVRPRRSEKSLKTREDI 70
            |....|.:|||||||||||:||||.:|.......|:|:|||:||:|
  Fly    17 DANTLFVDGERVLCFHGPLIYEAKVLKTKPDATPVEYYIHYAGWSK------------------- 62

Mouse    71 VALFPVPEGAPSVHHPLLTSSWDEWVPESRVLKYVDTNLQKQREL-------------------- 115
                                :|||||||:|||||.|.|:::::||
  Fly    63 --------------------NWDEWVPENRVLKYNDDNVKRRQELARQCGERSKKDNKKGVYIPG 107

Mouse   116 -QKANQEQYAEGKMRGAAPGKKTSGLQQKNVEVKT------------------------------ 149
             .||.:.:....:.|.:.|.|.::..|.......|
  Fly   108 SAKAKKMEQMRNESRASTPSKDSNTSQSTASSTPTTSAGPGSKSEAGSTGTTTTNSTANSTTSRA 172

Mouse   150 -KKNKQKTPGNGDGGSTS--------------ETPQPPRKKR----------------------- 176
             :|:.|.||.....|:.|              |.|..|:|||
  Fly   173 HRKSTQSTPSTARPGTPSDKKEDPAAAETTEEEGPVAPKKKRMSEQRPSLTGSDVAEKPLPPTTT 237

Mouse   177 -----ARVDPTVENEETFMNRVEVKVKIPEELKPWLVDDWDLITRQKQLFYLPAKKNVDSILEDY 236
                 ....|.||:||.:..:||||:|||:|||.:|.|||..:.|:.:|..||||..|..|.|.|
  Fly   238 PSTPTTEPAPCVESEEAYAAKVEVKIKIPDELKHYLTDDWYAVVREHKLLELPAKVTVQQISEQY 302

Mouse   237 ANYKKS-RGNTDNKEYAVNEVVAGIKEYFNVMLGTQLLYKFERPQYAEILADHPDAPMSQVYGAP 300
            ..:||| :..:.:||.|:|:|:.||.||||||||:||||||||.|||:::..|||.|:|::||:.
  Fly   303 LAHKKSVKSTSASKEVAINDVLDGIVEYFNVMLGSQLLYKFERTQYADVMQKHPDTPLSELYGSF 367

Mouse   301 HLLRLFVRIGAMLAYTPLDEKSLALLLNYLHDFLKYLAKNSATLFSASDYEVAPPEYHRKA 361
            ||||||||:|:||:|:.||::|:..||.::.||||:|.|||:..||.|::....|||.|.|
  Fly   368 HLLRLFVRLGSMLSYSALDQQSMQNLLTHVQDFLKFLVKNSSIFFSMSNFINVDPEYVRNA 428

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Morf4l1	NP_001034236.1	CBD_MSL3_like	15..110	CDD:350846	37/94 (39%)
		Interaction with KAT8. /evidence=ECO:0000250	26..62		13/35 (37%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	113..182		21/162 (13%)
		Sufficient for interaction with SIN3A. /evidence=ECO:0000250	133..266		58/206 (28%)
		Nuclear localization signal. /evidence=ECO:0000255	135..146		2/10 (20%)
		Interaction with RB1-1. /evidence=ECO:0000250	164..230		32/107 (30%)
		MRG	176..351	CDD:461721	94/203 (46%)
		Sufficient for interaction with PHF12. /evidence=ECO:0000250	188..342		84/154 (55%)
		Interaction with RB1-2. /evidence=ECO:0000250	323..344		10/20 (50%)
MRG15	NP_001262588.1	CBD_MSL3_like	26..82	CDD:350846	37/94 (39%)
		MRG	250..419	CDD:461721	91/168 (54%)