DRSC/TRiP Functional Genomics Resources

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Protein Alignment Alyref and CG18259

DIOPT Version :9

Sequence 1:NP_035698.1 Gene:Alyref / 21681 MGIID:1341044 Length:255 Species:Mus musculus
Sequence 2:NP_573324.1 Gene:CG18259 / 32866 FlyBaseID:FBgn0030956 Length:474 Species:Drosophila melanogaster


Alignment Length:200 Identity:56/200 - (28%)
Similarity:78/200 - (39%) Gaps:49/200 - (24%)


- Green bases have known domain annotations that are detailed below.


Mouse     4 KMDMSLDDIIKLNRSQRGGRGGGRGRGRAGSQGGRGGAVQAAARVNRGGGPMRNRPAIARGAAGG 68
            |.|..:...|..|.::|...|||   |...|..|......|||       |.:|:          
  Fly   304 KRDPHISHGIYANENRRKAVGGG---GARDSDSGTDSDGDAAA-------PSKNK---------- 348

Mouse    69 GRNRPAPYS-RPKQLPDKWQHDLFDSGFGGGAGVETGGKLLVSNLDFGVSDADIQELFAEFGTLK 132
             |..|:|.| |.....|                   |.:||||||...|:.|||:|||::.|.: 
  Fly   349 -RRSPSPLSLRTSNTKD-------------------GYRLLVSNLHTNVTTADIRELFSDIGPV- 392

Mouse   133 KAAVHYDRSGRSLGTADVHFERKADALKAMKQYNGVPLDGRPMNIQLVTSQIDTQRRPAQSINRG 197
                 ||......|||:|.::....|.||:..|:....|.:||:..||...  :.||.....:..
  Fly   393 -----YDARVVRPGTAEVIYKSLEHAEKAVDTYHHRQFDDQPMHCVLVNPH--SSRRSVHKASSR 450

Mouse   198 GMTRN 202
            .:|.|
  Fly   451 TVTTN 455

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
AlyrefNP_035698.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..83 21/79 (27%)
Sufficient for RNA-binding, interaction with NXF1-NXT1 heterodimer. /evidence=ECO:0000250 16..37 7/20 (35%)
RRM_THOC4 106..179 CDD:241124 27/72 (38%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 185..255 3/17 (18%)
CG18259NP_573324.1 RRM <345..>443 CDD:223796 38/135 (28%)
RRM_SKAR 366..434 CDD:241125 27/73 (37%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0533
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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