Protein Alignment Slc5a8 and CG32669

DIOPT Version :9

• Sequence 1: NP_663398.2
• Gene: Slc5a8 / 216225
• MGIID: 2384916
• Length: 611
• Species: Mus musculus
• Sequence 2: NP_727460.1
• Gene: CG32669 / 326229
• FlyBaseID: FBgn0052669
• Length: 604
• Species: Drosophila melanogaster
• Alignment Length: 607
• Identity: 252/607 - (41%)
• Similarity: 357/607 - (58%)
• Gaps: 40/607 - (6%)

Mouse    13 WDYVVFAGMLLISAAIGIYYAFAGGGQQTSKDFLMGGRSMSAVPVALSLTASFMSAVTVLGTPAE 77
            |||.:.|.:|:||.||||||.|.||.|.|:.::|:..|||:..|||.||.||||||||:||...|
  Fly     7 WDYTILAVVLIISVAIGIYYRFVGGKQSTTTEYLLADRSMNVAPVAFSLMASFMSAVTILGVSME 71

Mouse    78 VYRFGAIFSIFVITYFFVVVISAEVFLPVFYRLGITSTYEYLELRFNRCIRLCGTILFIVQTILY 142
            .|::|.:|.:..::|.....::|.:.:||||||...|.||||||||....||..::.|.:|.:||
  Fly    72 NYQYGTMFVVINLSYVLSTPVAAYLIIPVFYRLKTASVYEYLELRFGYATRLAASLSFSLQMVLY 136

Mouse   143 TGIVIYAPALALNQVTGFDLWGAVVATGVVCTFYCTLGGLKAVVWTDVFQVGIMVAGFASVIIQA 207
            .|||:|||||||..|||.....::|..|||||||.||||:|||:.||::|..:|.|...||||.|
  Fly   137 MGIVVYAPALALEAVTGLSQVFSIVIVGVVCTFYATLGGMKAVLITDIYQSLLMFAAVFSVIICA 201

Mouse   208 SITQHGINKILSDAFNGGRLNFWNFDPNPLQRHTFWTIVIGGTFTWTTIYGVNQSQVQRYISCKS 272
            .:....:..|...|...||:|..||..:|.:|||::|.::||..|:..||||||:||||.::.||
  Fly   202 WVKAGSLEVIWRVAQENGRINLTNFSVDPTERHTWFTQILGGCATYLAIYGVNQTQVQRLMAVKS 266

Mouse   273 RLHAKLSLYVNLVGLWVILTCSIFCGLALYSRYRECDPWTSKKVSAIDQLMPYLVLDILKNYPGV 337
            ...|:.:|:..|..|.::...:.|.||.:|..||:|||....:|::.||:||..|:|.:..|.|:
  Fly   267 LSAARAALWWCLPILCLLSLSTCFSGLCIYWYYRDCDPLLEGRVNSRDQVMPLFVVDTMGEYTGL 331

Mouse   338 PGLFVACAYSGTLSTVSSSINALAAVTVEDLIKPRF-----KSLSEKSLSWISQGMSVLYGALCI 397
            .||||:..:..:|||:||.|::|||||:||.:||..     ::|:::...|.|:.:|:.:|||||
  Fly   332 AGLFVSGIFCASLSTISSIISSLAAVTLEDYLKPLVSCCAKRTLTDRQTLWYSKLLSLFFGALCI 396

Mouse   398 GMAALASLMGALLQAALSIFGMVGGPLLGLFSLGILVPFANSIGALTGLLAGFAISLWVGIGAQL 462
            |||.:|..:|.||||||||||::||||||||:||:.|..||..||:.|||...|...|:|.| |.
  Fly   397 GMAFMAGSIGGLLQAALSIFGIIGGPLLGLFTLGMYVTKANEKGAIGGLLISLAFCFWIGFG-QP 460

Mouse   463 YPPLPERTLPLPLETYGCNITHNGSDWMSTTEMPFSTSAFQIHNAERTPLMDNWYSLSYLYFSTI 527
            .|||    :.|.:.|.||.:..      |.....|..:...:...|....:   |.:||::::.:
  Fly   461 KPPL----VSLDMSTAGCPVDR------SFARDIFLKTVIAVAEEEHYFYL---YRISYMWYAAL 512

Mouse   528 GTLTTLFVGILISLSTGGRKQNLDPRFLLTKQDFLSNFDVF----KKRNHVLNYKLHPV------ 582
            |.|.|.|.|.|:|......|.:.:.|........|...|:|    .||   |..:..|:
  Fly   513 GFLITFFGGWLLSWLFALLKWDNNRRIYQDADCTLIKHDLFVPPIAKR---LQRRQMPLLVVTGT 574

Mouse   583 --EVGG------TDNPAFNHVE 596
              |:||      |..|..:.:|
  Fly   575 SSEIGGITTESATAPPRLDEIE 596

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Slc5a8	NP_663398.2	SLC5sbd_SMCT1	7..549	CDD:271402	238/540 (44%)
CG32669	NP_727460.1	SLC5sbd_NIS-SMVT	7..527	CDD:271383	237/533 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	366	1.000	Domainoid score	I922
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H64832
Inparanoid	1	1.050	431	1.000	Inparanoid score	I1711
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D489472at33208
OrthoFinder	1	1.000	-	-		FOG0000151
OrthoInspector	1	1.000	-	-		mtm8902
orthoMCL	1	0.900	-	-		OOG6_101204
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6277
SonicParanoid	1	1.000	-	-		X112
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	11.800