Protein Alignment F11 and CG10232

DIOPT Version :10

• Sequence 1: XP_005262878.1
• Gene: F11 / 2160
• HGNCID: 3529
• Length: 626
• Species: Homo sapiens
• Sequence 2: NP_651175.4
• Gene: CG10232 / 42800
• FlyBaseID: FBgn0039108
• Length: 509
• Species: Drosophila melanogaster
• Alignment Length: 505
• Identity: 136/505 - (26%)
• Similarity: 199/505 - (39%)
• Gaps: 155/505 - (30%)

Human   230 CTHHPGCLFFTFFSQ----EWPKESQRNLCLLKTSESGLPSTRIKKSKALSGFSLQSCRHSIPVF 290
            |||...|....:|.|    .|.:|:     :|:..:.|..|...:|    .|:..:|....:
  Fly    39 CTHLKACPPLKYFLQSADISWAREA-----ILRDKQCGYNSYCCRK----EGYERRSNEQCV--- 91

Human   291 CHSSFYHD-TDFLGEE--LDIVAAKSHEAC-----QKLCTNA--VRCQFFTYTPAQAS--CNEGN 343
                ..:| ..|.|.:  .||:.:..::.|     |.|....  |.||.....|.|..  |.  :
  Fly    92 ----MLNDCPQFNGRKWTSDILKSIINKICYIDHFQPLVRRRVYVNCQRQEIFPCQYDEICR--S 150

Human   344 RGKC-YLKLSSNGSPTKILHGRGGISGY---------------TLRLCK---------------M 377
            |..| :|||....:...::..:.||:.|               .:||.|               |
  Fly   151 RDSCPFLKLKRKKAQNILMSRQCGINTYCCPKQEFPDCPADEKCIRLDKCLRIHNTTMEDGANLM 215

Human   378 DN-EC---TTKI-----------KP---------------RIVGGTASVRGEWPWQVTL---HTT 409
            || :|   |.:|           :|               |:..|||:...|:||...|   :..
  Fly   216 DNRQCAIDTRRIDSDKRHYICCPEPGNVLPTSCGQAPPLYRMAYGTAARPNEYPWMAMLIYENRR 280

Human   410 SPTQRHLCGGSIIGNQWILTAAHCFYG---VESPKILRVYSGILNQSEI--KEDTSF-------- 461
            ..|..:.|.||:|..:::||||||...   |.:..:||...  |.:.:|  ..|..|
  Fly   281 LSTMTNNCSGSLINKRYVLTAAHCVVKDKMVNTDLVLRRVR--LGEHDITTNPDCDFTGNCAAPF 343

Human   462 --FGVQEIIIHDQY---KMAESGYDIALLKLETTVNYTDSQRPICLPSKGDRNVIYT-DCWVTGW 520
              .|::...:|:||   ...||  ||||::|:|.|.||....|||:|.  |...::. ...:.||
  Fly   344 VEIGIEYFNVHEQYFNTSRFES--DIALVRLQTPVRYTHEILPICVPK--DPIPLHNHPLQIAGW 404

Human   521 GYRKLRDKIQ----NTLQ------KAKIPLVTNEECQKRYRGHKITHKMICA-GYREGGKDACKG 574
            ||.|.|:..|    ||:.      :.||....||             ..||| |.|  |:|:|:|
  Fly   405 GYTKNREYSQVLLHNTVYENRYYCQDKISFFRNE-------------SQICASGIR--GEDSCEG 454

Human   575 DSGGPLSCKHN----EVWHLVGITSWG-EGCAQRERPGVYTNVVEYVDWI 619
            ||||||....|    ::.:|.||.|:| |.|..| :|||||....:..||
  Fly   455 DSGGPLMLTLNNDYQDIVYLAGIVSYGSENCGDR-KPGVYTKTGAFFSWI 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
F11	XP_005262878.1	APPLE	20..103	CDD:128519
		APPLE	110..193	CDD:128519
		APPLE	200..283	CDD:128519	13/56 (23%)
		APPLE	291..375	CDD:128519	23/111 (21%)
		Tryp_SPc	389..619	CDD:238113	87/267 (33%)
CG10232	NP_651175.4	Tryp_SPc	260..506	CDD:238113	89/266 (33%)