Protein Alignment F11 and CG31266

DIOPT Version :10

• Sequence 1: XP_005262878.1
• Gene: F11 / 2160
• HGNCID: 3529
• Length: 626
• Species: Homo sapiens
• Sequence 2: NP_001138068.1
• Gene: CG31266 / 42071
• FlyBaseID: FBgn0051266
• Length: 282
• Species: Drosophila melanogaster
• Alignment Length: 286
• Identity: 83/286 - (29%)
• Similarity: 131/286 - (45%)
• Gaps: 41/286 - (14%)

Human   349 LKLSSNGSPTKILHGRG-GISGYTLRLCKMDNECTTKIKP--RIVGGTASVRGEWPWQVTLHTTS 410
            |.|.:...||:.:..|| .:.|    |..::...:|:..|  |::|||.:..|.|||..::.  :
  Fly    13 LTLLALQGPTEAMRMRGEPLPG----LANIERHRSTEAVPQGRVIGGTTAAEGNWPWIASIQ--N 71

Human   411 PTQRHLCGGSIIGNQWILTAAHCFYGVESPKILRVYSGILNQSEIKEDTSFFGVQEIIIHDQYKM 475
            ....||||..|:...|:||||.|..|:. |..|.|.:|.::..::.  ..::.|.:|.:|..:..
  Fly    72 AYSYHLCGAIILDETWVLTAASCVAGLR-PLNLLVVTGTVDWWDLY--APYYTVSQIHVHCNFDK 133

Human   476 AESGYDIALLKLETTVNYTDSQRPICLP-----SKGDRNVIYTDCWVTGWGYRKLRDKIQNTLQK 535
            .....|||||:|.:.:.:.|..:.|.|.     .:||:...      .|||..:........||:
  Fly   134 PLYHNDIALLQLSSKIEFNDVTKNITLADIDELEEGDKLTF------AGWGSSEAMGTYGRYLQE 192

Human   536 AKIPLVTNEECQKRYR-------GHKITHKMICAGYREGGKDACKGDSGGPLSCKHNEVWHLVGI 593
            |....:..:.|:::.:       ||      :|. ..:.|:.||.||:||||.   :|...||||
  Fly   193 ASGTYLPVDACREKLQNQDDVDLGH------VCV-QMDAGQGACHGDTGGPLI---DEQQRLVGI 247

Human   594 TSWGEGCAQRERPGVYTNVVEYVDWI 619
            .:||..|. |..|.||.....|.|||
  Fly   248 GNWGVPCG-RGYPDVYARTAFYHDWI 272

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
F11	XP_005262878.1	APPLE	20..103	CDD:128519
		APPLE	110..193	CDD:128519
		APPLE	200..283	CDD:128519
		APPLE	291..375	CDD:128519	7/26 (27%)
		Tryp_SPc	389..619	CDD:238113	70/241 (29%)
CG31266	NP_001138068.1	Tryp_SPc	52..275	CDD:238113	72/243 (30%)