Protein Alignment F11 and Sb

DIOPT Version :10

• Sequence 1: XP_005262878.1
• Gene: F11 / 2160
• HGNCID: 3529
• Length: 626
• Species: Homo sapiens
• Sequence 2: NP_476709.1
• Gene: Sb / 41958
• FlyBaseID: FBgn0003319
• Length: 787
• Species: Drosophila melanogaster
• Alignment Length: 272
• Identity: 100/272 - (36%)
• Similarity: 148/272 - (54%)
• Gaps: 20/272 - (7%)

Human   366 GISGYTLRLCKMDNEC--TTKIKP--RIVGGTASVRGEWPWQVTLHTTS---PTQRHLCGGSIIG 423
            |..|:...:....:||  .|..:|  |||||.::..|.|||||::..||   .:..|.|||::|.
  Fly   517 GALGHVKTISAARSECGVPTLARPETRIVGGKSAAFGRWPWQVSVRRTSFFGFSSTHRCGGALIN 581

Human   424 NQWILTAAHCFYGVESPKI--LRVYSGILNQSEIKEDTSFF--GVQEIIIHDQYKMAESGYDIAL 484
            ..||.||.||   |:...|  :|:..|..:.|.::|...:.  ||.:.::|.:|......||:||
  Fly   582 ENWIATAGHC---VDDLLISQIRIRVGEYDFSHVQEQLPYIERGVAKKVVHPKYSFLTYEYDLAL 643

Human   485 LKLETTVNYTDSQRPICLPSKGDRNVIYTDCWVTGWGYRKLRDKIQNTLQKAKIPLVTNEECQKR 549
            :|||..:.:.....||||| :.|..:|..:..|||||.......:.:.||:..:|:|:|:.|:..
  Fly   644 VKLEQPLEFAPHVSPICLP-ETDSLLIGMNATVTGWGRLSEGGTLPSVLQEVSVPIVSNDNCKSM 707

Human   550 Y----RGHKITHKMICAGYREGGKDACKGDSGGPLSCKHNE-VWHLVGITSWGEGCAQRERPGVY 609
            :    |...|....:||||..||:|:|:|||||||..|..: .:.|.||.|||.|||:...|||.
  Fly   708 FMRAGRQEFIPDIFLCAGYETGGQDSCQGDSGGPLQAKSQDGRFFLAGIISWGIGCAEANLPGVC 772

Human   610 TNVVEYVDWILE 621
            |.:.::..||||
  Fly   773 TRISKFTPWILE 784

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
F11	XP_005262878.1	APPLE	20..103	CDD:128519
		APPLE	110..193	CDD:128519
		APPLE	200..283	CDD:128519
		APPLE	291..375	CDD:128519	2/8 (25%)
		Tryp_SPc	389..619	CDD:238113	89/241 (37%)
Sb	NP_476709.1	Tryp_SPc	544..785	CDD:238113	93/245 (38%)