Protein Alignment F11 and CG4613

DIOPT Version :10

• Sequence 1: XP_005262878.1
• Gene: F11 / 2160
• HGNCID: 3529
• Length: 626
• Species: Homo sapiens
• Sequence 2: NP_648707.2
• Gene: CG4613 / 39586
• FlyBaseID: FBgn0036427
• Length: 374
• Species: Drosophila melanogaster
• Alignment Length: 339
• Identity: 106/339 - (31%)
• Similarity: 174/339 - (51%)
• Gaps: 47/339 - (13%)

Human   299 TDFLGEELDIVAAKSHEACQKLCTNAVRCQFFTYTPAQASCNEGNRGKCYLKLSSNGSPTKILHG 363
            :||:.:.::     .|:  |::.:|.:...  :.||:..:.:.|:     ..|||:.||...|.|
  Fly    63 SDFIDDLIE-----GHK--QQILSNVLGVA--SETPSDTASSLGS-----TSLSSSASPVFPLEG 113

Human   364 RGGISGYTLRLCKMDNECTTKIK--PRIVGGTASVRGEWPW--QVTLHTTSPTQRHLCGGSIIGN 424
             ||...:.:..|.   .||..:.  .||||||.....::||  |:...|..     .|||::|.:
  Fly   114 -GGAKAFRVNRCA---SCTCGVPNVNRIVGGTQVRTNKYPWIAQIIRGTFL-----FCGGTLIND 169

Human   425 QWILTAAHCFYGVE----SPKILRVYSGILNQSEIKEDTSFFGVQEII----IHDQYKMAESGYD 481
            :::||||||.:|::    |.::|          ::...::..||...:    .|..|......:|
  Fly   170 RYVLTAAHCVHGMDMRGVSVRLL----------QLDRSSTHLGVTRSVAFAHAHVGYDPVSLVHD 224

Human   482 IALLKLETTVNYTDSQRPICLPSKGDRNVIYTDCWVTGWGYRKLRDKIQNTLQKAKIPLVTNEEC 546
            ||||:|:..:...|:.||.||||...:|..:....|.|||..:......:.||:..:|::||.:|
  Fly   225 IALLRLDQPIPLVDTMRPACLPSNWLQNFDFQKAIVAGWGLSQEGGSTSSVLQEVVVPIITNAQC 289

Human   547 QKRYRGHKITHKMICAGY-REGGKDACKGDSGGPLSCKHNEVWHLVGITSWGEGCAQRERPGVYT 610
            :.......|...|:|||| :.||:|||:|||||||..: :.::.|.|:.|:|.|||:.:.|||||
  Fly   290 RATSYRSMIVDTMMCAGYVKTGGRDACQGDSGGPLIVR-DRIFRLAGVVSFGYGCAKPDAPGVYT 353

Human   611 NVVEYVDWILEKTQ 624
            .|..|::||...|:
  Fly   354 RVSRYLEWIAVNTR 367

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
F11	XP_005262878.1	APPLE	20..103	CDD:128519
		APPLE	110..193	CDD:128519
		APPLE	200..283	CDD:128519
		APPLE	291..375	CDD:128519	17/75 (23%)
		Tryp_SPc	389..619	CDD:238113	82/240 (34%)
CG4613	NP_648707.2	Tryp_SPc	136..362	CDD:214473	83/241 (34%)