Protein Alignment F11 and CG10472

DIOPT Version :10

• Sequence 1: XP_005262878.1
• Gene: F11 / 2160
• HGNCID: 3529
• Length: 626
• Species: Homo sapiens
• Sequence 2: NP_648017.1
• Gene: CG10472 / 38688
• FlyBaseID: FBgn0035670
• Length: 290
• Species: Drosophila melanogaster
• Alignment Length: 285
• Identity: 89/285 - (31%)
• Similarity: 129/285 - (45%)
• Gaps: 44/285 - (15%)

Human   356 SPTKILHGRGGISGYTLRLCKMDNECTTKIKPRIVGGTASVRGEWPWQVTLHTTSPTQRHLCGGS 420
            :|...:||....||                  ||.||..:...::|:||.|..........|||:
  Fly    32 TPMPKVHGETLPSG------------------RITGGQIAEPNQFPYQVGLLLYITGGAAWCGGT 78

Human   421 IIGNQWILTAAHC----FYGVESPKILRVYSGILNQSEIKEDTS---FFGVQEIIIHDQYKMAES 478
            ||.::||:|||||    ..||:      ||.|..:::..||:..   |...:.:|:|:.:.....
  Fly    79 IISDRWIITAAHCTDSLTTGVD------VYLGAHDRTNAKEEGQQIIFVETKNVIVHEDWIAETI 137

Human   479 GYDIALLKLETTVNYTDSQRPICLPSKGDRNVIY--TDCWVTGWGYRKLRDK---IQNTLQKAKI 538
            ..||:|:||...:.:....:|..||.|.|....|  .:...:|||  |:.|.   ..:.||.|.:
  Fly   138 TNDISLIKLPVPIEFNKYIQPAKLPVKSDSYSTYGGENAIASGWG--KISDSATGATDILQYATV 200

Human   539 PLVTNEECQKRYRGHKITHKMICAGYREGGKDACKGDSGGPLSCKHNEVWHLVGITSWG--EGCA 601
            |::.|..|...|.| .:....||. ...||...|.|||||||....... .|:|.||:|  .||
  Fly   201 PIMNNSGCSPWYFG-LVAASNICI-KTTGGISTCNGDSGGPLVLDDGSN-TLIGATSFGIALGC- 261

Human   602 QRERPGVYTNVVEYVDWILEKTQAV 626
            :...|||:|.:..|:|||.||:..|
  Fly   262 EVGWPGVFTRITYYLDWIEEKSGVV 286

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
F11	XP_005262878.1	APPLE	20..103	CDD:128519
		APPLE	110..193	CDD:128519
		APPLE	200..283	CDD:128519
		APPLE	291..375	CDD:128519	5/18 (28%)
		Tryp_SPc	389..619	CDD:238113	78/243 (32%)
CG10472	NP_648017.1	Tryp_SPc	46..279	CDD:214473	79/244 (32%)