Protein Alignment F11 and CG6462

DIOPT Version :10

• Sequence 1: XP_005262878.1
• Gene: F11 / 2160
• HGNCID: 3529
• Length: 626
• Species: Homo sapiens
• Sequence 2: NP_648011.1
• Gene: CG6462 / 38681
• FlyBaseID: FBgn0035663
• Length: 319
• Species: Drosophila melanogaster
• Alignment Length: 279
• Identity: 88/279 - (31%)
• Similarity: 132/279 - (47%)
• Gaps: 36/279 - (12%)

Human   366 GISGYTLRLCK--MDNECTTKIKPRIVGGTASVRGEWPWQVTL-HTTSPTQRHLCGGSIIGNQWI 427
            |...:.||..|  |:...|..::.||.||..:.||.:|:||.| ...|......||||:|..|::
  Fly    52 GYENFRLRCEKFEMEGNQTAAVRTRIAGGELATRGMFPYQVGLVIQLSGADLVKCGGSLITLQFV 116

Human   428 LTAAHCFYGVESPKILRVYSGILNQSEIKEDTSFFGV--QEIIIHDQYKMAESGY-DIALLKLET 489
            ||||||.....:.||   |:|....:::::......|  ::.||:..| :...|| |:||::|..
  Fly   117 LTAAHCLTDAIAAKI---YTGATVFADVEDSVEELQVTHRDFIIYPDY-LGFGGYSDLALIRLPR 177

Human   490 TVNYTDSQRPICLPSKGDRNVIYTDCWVT--GWGY-RKLRDKIQNTLQKAKIPLVTNEEC----- 546
            .|..::..:||.|..:...........||  |||| ....||....||.....::..|.|
  Fly   178 KVRTSEQVQPIELAGEFMHQNFLVGKVVTLSGWGYLGDSTDKRTRLLQYLDAEVIDQERCICYFL 242

Human   547 -----QKRYRGHKITHKMICAGYREGGKDACKGDSGGPLSCKHNEVWHLVGITSWG--EGCAQRE 604
                 |:|:         :|.. ...|:.||.||||||:......|.:|:|:||:|  ||| :..
  Fly   243 PGLVSQRRH---------LCTD-GSNGRGACNGDSGGPVVYHWRNVSYLIGVTSFGSAEGC-EVG 296

Human   605 RPGVYTNVVEYVDWILEKT 623
            .|.|||.:..|:.||.::|
  Fly   297 GPTVYTRITAYLPWIRQQT 315

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
F11	XP_005262878.1	APPLE	20..103	CDD:128519
		APPLE	110..193	CDD:128519
		APPLE	200..283	CDD:128519
		APPLE	291..375	CDD:128519	3/8 (38%)
		Tryp_SPc	389..619	CDD:238113	78/248 (31%)
CG6462	NP_648011.1	Tryp_SPc	77..314	CDD:238113	80/251 (32%)