Protein Alignment F11 and CG3700

DIOPT Version :10

• Sequence 1: XP_005262878.1
• Gene: F11 / 2160
• HGNCID: 3529
• Length: 626
• Species: Homo sapiens
• Sequence 2: NP_611736.1
• Gene: CG3700 / 37640
• FlyBaseID: FBgn0034796
• Length: 360
• Species: Drosophila melanogaster
• Alignment Length: 273
• Identity: 86/273 - (31%)
• Similarity: 128/273 - (46%)
• Gaps: 33/273 - (12%)

Human   375 CKMDNECTTKIK--PRIVGGTASVRGEWPWQVTLHTTSPTQRHL-----CGGSIIGNQWILTAAH 432
            ||..||..:..:  |.|||||.:...|:|:...:.|..|.:...     ||||::..:::|||||
  Fly    86 CKQYNEVRSACQSTPFIVGGTKASGKEFPFMALIGTHRPNKSKSDINWDCGGSVVHPKFVLTAAH 150

Human   433 CFY-----------GVESPKILRVYSGILNQSEIKED--TSFFGVQEIIIHDQY--KMAESGY-- 480
            |..           ..:|||.: |..|.|:.:...:|  ...|.|...::|..|  :..|.|:
  Fly   151 CLETDESKAERLDPNFDSPKFV-VRLGELDYNSTTDDALVQDFRVVNYVVHPGYDTEDEEQGFKN 214

Human   481 DIALLKLETTVNYTDSQRPICLPSKGDRNVIYTDCWVTGWGYRKLRDKIQNT-LQKAKIPLVTNE 544
            ||||::|:....:.|....:|||.....:|  ......|||:  ..|.:::: |.|..:...::|
  Fly   215 DIALVELDRKAEFNDHVAAVCLPPDSGNDV--QQVTAAGWGF--TADGVKSSHLLKVNLQRFSDE 275

Human   545 ECQKRYRGHKITHKMICAGYREGGKDACKGDSGGPLSCKHNE---VWHLVGITSWGEGCAQRERP 606
            .||||.|....|....|||......|.|.||||||:..:|..   :..::||.|:|..|..:..|
  Fly   276 VCQKRLRFSIDTRTQFCAGSMSSQADTCNGDSGGPIFVQHPLYPCLKQVIGIVSYGLVCGSQGLP 340

Human   607 GVYTNVVEYVDWI 619
            .|||.|..|.|||
  Fly   341 SVYTKVHLYTDWI 353

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
F11	XP_005262878.1	APPLE	20..103	CDD:128519
		APPLE	110..193	CDD:128519
		APPLE	200..283	CDD:128519
		APPLE	291..375	CDD:128519	86/273 (32%)
		Tryp_SPc	389..619	CDD:238113	79/255 (31%)
CG3700	NP_611736.1	Tryp_SPc	102..356	CDD:238113	81/257 (32%)