Protein Alignment F11 and iotaTry

DIOPT Version :10

• Sequence 1: XP_005262878.1
• Gene: F11 / 2160
• HGNCID: 3529
• Length: 626
• Species: Homo sapiens
• Sequence 2: NP_523695.1
• Gene: iotaTry / 36223
• FlyBaseID: FBgn0015001
• Length: 252
• Species: Drosophila melanogaster
• Alignment Length: 273
• Identity: 88/273 - (32%)
• Similarity: 129/273 - (47%)
• Gaps: 37/273 - (13%)

Human   366 GISGYTLRLCKMDNECTTKIKPRIVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTA 430
            ||....|.|..:.:....:...||:||:..:....||||::..::   ||.|||.|...:.|:||
  Fly     5 GIVATVLVLLLLGDASDVEATGRIIGGSDQLIRNAPWQVSIQISA---RHECGGVIYSKEIIITA 66

Human   431 AHCFYGVESPKILRVYSGILNQSEIKEDTSFFG-----VQEIIIHDQYKMAESGYDIALLKLETT 490
            .||.: ..|..:::|..|..|.:        :|     |....:|:|:......||||:|:|.|.
  Fly    67 GHCLH-ERSVTLMKVRVGAQNHN--------YGGTLVPVAAYKVHEQFDSRFLHYDIAVLRLSTP 122

Human   491 VNYTDSQRPICL----PSKGDRNVIYTDCWVTGWGYRKLRDKIQNTLQKAKIPLVTNEECQKR-- 549
            :.:..|.|.|.|    ||.|      |...|||||:.. ...:.::||||::.::...||..:
  Fly   123 LTFGLSTRAINLASTSPSGG------TTVTVTGWGHTD-NGALSDSLQKAQLQIIDRGECASQKF 180

Human   550 -YRGHKITHKMICAGYREGGKDACKGDSGGPLSCKHNEVWHLVGITSWGEGCAQRERPGVYTNVV 613
             |....:..:.|||...:.  |||.|||||||....    .||||.|||..||....||||.:|.
  Fly   181 GYGADFVGEETICAASTDA--DACTGDSGGPLVASS----QLVGIVSWGYRCADDNYPGVYADVA 239

Human   614 EYVDWILEKTQAV 626
            ....||::...|:
  Fly   240 ILRPWIVKAANAI 252

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
F11	XP_005262878.1	APPLE	20..103	CDD:128519
		APPLE	110..193	CDD:128519
		APPLE	200..283	CDD:128519
		APPLE	291..375	CDD:128519	3/8 (38%)
		Tryp_SPc	389..619	CDD:238113	80/241 (33%)
iotaTry	NP_523695.1	Tryp_SPc	27..245	CDD:214473	81/242 (33%)