Protein Alignment F11 and CG12133

DIOPT Version :10

• Sequence 1: XP_005262878.1
• Gene: F11 / 2160
• HGNCID: 3529
• Length: 626
• Species: Homo sapiens
• Sequence 2: NP_610540.2
• Gene: CG12133 / 36036
• FlyBaseID: FBgn0033469
• Length: 340
• Species: Drosophila melanogaster
• Alignment Length: 334
• Identity: 93/334 - (27%)
• Similarity: 139/334 - (41%)
• Gaps: 85/334 - (25%)

Human   359 KILHGRGGI----SGYTLRLCKM------------------------DNECTTKIKPR--IVGGT 393
            ||||.|...    |.|..:||.:                        |:....:..|.  ||||.
  Fly     2 KILHPRNMTNDQKSQYRNKLCNINPFAHELVHMVFTCCPMVAGDKLPDSRVCGQSPPSSYIVGGM 66

Human   394 ASVRGEWPWQVTL----HTTSPTQRHLCGGSIIGNQWILTAAHC-----FYGVESPKILRVYSGI 449
            .:...::||.|.|    :|.......:|.||:|.::::||||||     ||      :.||.
  Fly    67 EAQSNQFPWTVLLGYEAYTAKQRPSPMCAGSLIASRYVLTAAHCLNVNDFY------VARVR--- 122

Human   450 LNQSEIKEDTSF----------------FGVQEIIIHDQYKMAESGY--DIALLKLETTVNYTDS 496
            |.:.:.:.|..:                ..|...:.|:||......:  |||||:|::.|.||..
  Fly   123 LGEHDTENDPDYTWLPNGAKIWAPAHVDIDVDLRVPHEQYYTRNGRHYNDIALLRLKSRVKYTLQ 187

Human   497 QRPIC------LPSKGDRNVIYTDCWVTGWGYRKLRDKIQNTLQKAKIPLVTNEECQKRYRGHKI 555
            .||||      |.:...:|..:.   :.|||...|:.| ...|::..|..::.:||..||....:
  Fly   188 IRPICIWPGIELSTSSFKNFPFQ---IAGWGDSGLQQK-STVLRQGTISGMSPDECLNRYPTLLV 248

Human   556 THKM-ICA-GYREGGKDACKGDSGGPLSCK----HNEVWHLVGITSWGEG-CAQRERPGVYTNVV 613
            ...: ||| |:  .|.|...||||.||...    .::.::|.||||:|.| .:....|.|||...
  Fly   249 DKDIQICAMGW--DGTDTGLGDSGSPLMASVGRGADQFYYLAGITSYGGGPSSYGYGPAVYTKTS 311

Human   614 EYVDWILEK 622
            .|.:||.:|
  Fly   312 SYYEWIKKK 320

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
F11	XP_005262878.1	APPLE	20..103	CDD:128519
		APPLE	110..193	CDD:128519
		APPLE	200..283	CDD:128519
		APPLE	291..375	CDD:128519	7/19 (37%)
		Tryp_SPc	389..619	CDD:238113	79/269 (29%)
CG12133	NP_610540.2	Tryp_SPc	62..317	CDD:214473	79/269 (29%)