Protein Alignment F11 and Phae1

DIOPT Version :10

• Sequence 1: XP_005262878.1
• Gene: F11 / 2160
• HGNCID: 3529
• Length: 626
• Species: Homo sapiens
• Sequence 2: NP_609550.1
• Gene: Phae1 / 34637
• FlyBaseID: FBgn0263234
• Length: 270
• Species: Drosophila melanogaster
• Alignment Length: 283
• Identity: 81/283 - (28%)
• Similarity: 124/283 - (43%)
• Gaps: 28/283 - (9%)

Human   353 SNGSPTKILHGRGGISGYTLRL--CKMDNECTTKIKPRIVGGTASVRGEWPWQVTLHTTSPTQRH 415
            :||..||.|     .||..|.|  |::........:.|:|||:.:.....|:.|::....   .|
  Fly     3 ANGQQTKSL-----ASGLLLLLGICRISGVAIGAPEGRVVGGSPAAVNSAPYAVSMQYGG---TH 59

Human   416 LCGGSIIGNQWILTAAHCFYGVESPKIL--RVYSGILNQSEIKEDTSFFGVQEIIIHDQYKMAES 478
            .|..||:...|::|||||.  ..|.::|  .:.:|.:........|....:...:|:|.|.....
  Fly    60 YCAASILNANWLVTAAHCL--TNSNQVLGSTLVAGSIAVDGTASTTQTRSITYFVINDLYTGGTV 122

Human   479 GYDIALLKLETTVNYTDSQRPICLPSKGDRNVIYT-DCWVTGWGYRKLRD--KIQNTLQKA-KIP 539
            .|||.::...|...::.:..|:.|||.|   |:.| ...:.|||.....:  ...:|||.| .:|
  Fly   123 PYDIGMIYTPTAFVWSAAVAPVTLPSSG---VVPTGTANLYGWGSTSTTNTASYPSTLQVATNVP 184

Human   540 LVTNEECQKRY--RGHKITHKMICAGYREGGKDACKGDSGGPLSCKHNEVWHLVGITSWGE-GCA 601
            :::...|:...  :|..:....:|.|...||...|..||||||  ....|  |:||.|||: .|.
  Fly   185 IISLSSCESALGTKGSDVHSTNLCTGPLTGGVSICTSDSGGPL--VQGNV--LIGIVSWGKLPCG 245

Human   602 QRERPGVYTNVVEYVDWILEKTQ 624
            |...|.||..|..::.||....|
  Fly   246 QANSPSVYVQVSSFISWISANQQ 268

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
F11	XP_005262878.1	APPLE	20..103	CDD:128519
		APPLE	110..193	CDD:128519
		APPLE	200..283	CDD:128519
		APPLE	291..375	CDD:128519	9/23 (39%)
		Tryp_SPc	389..619	CDD:238113	67/238 (28%)
Phae1	NP_609550.1	Tryp_SPc	36..266	CDD:238113	69/241 (29%)