Protein Alignment F11 and CG1304

DIOPT Version :10

• Sequence 1: XP_005262878.1
• Gene: F11 / 2160
• HGNCID: 3529
• Length: 626
• Species: Homo sapiens
• Sequence 2: NP_608418.1
• Gene: CG1304 / 33074
• FlyBaseID: FBgn0031141
• Length: 260
• Species: Drosophila melanogaster
• Alignment Length: 272
• Identity: 74/272 - (27%)
• Similarity: 121/272 - (44%)
• Gaps: 47/272 - (17%)

Human   367 ISGYTLRLCKMDNECTTKIKPRIVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAA 431
            :..:.|.|....:.....:..|:|||..:|:.::|.||:|....   .|.|||||:...::||||
  Fly    10 LGSFLLLLAVPVHSAPGSLNGRVVGGEDAVKNQFPHQVSLRNAG---SHSCGGSILSRNYVLTAA 71

Human   432 HCF----------------YGVESPKILRVYSGILNQSEIKEDTSFFGVQEIIIHDQYKMAESGY 480
            ||.                :.:.:....|...|:|.|           |.|:|:|::|  .....
  Fly    72 HCVTNQDSNGNSVPIAAERFTIRAGSNDRFSGGVLVQ-----------VAEVIVHEEY--GNFLN 123

Human   481 DIALLKLETTVNYTDSQRPICLP---SKGDRNVIYTDCWVTGWGYRKLRDKIQNTLQKAKIPLVT 542
            |:|||:||:.:..:.|.:||.||   :..|.:||     ::|||..|.:..:...||...:..::
  Fly   124 DVALLRLESPLILSASIQPIDLPTADTPADVDVI-----ISGWGRIKHQGDLPRYLQYNTLKSIS 183

Human   543 NEECQKRYRGHKITHKMICAGYREGGKDACKGDSGGPLSCKHNEVWHLVGITSWGEGCAQRERPG 607
            .|.|.:.. |..:..: :|. ..|....||.|||||| :..:|:|   ||:..:.........|.
  Fly   184 LERCDELI-GWGVQSE-LCL-IHEADNGACNGDSGGP-AVYNNQV---VGVAGFVWSACGTSYPD 241

Human   608 VYTNVVEYVDWI 619
            .|..|..:.:||
  Fly   242 GYARVYYHNEWI 253

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
F11	XP_005262878.1	APPLE	20..103	CDD:128519
		APPLE	110..193	CDD:128519
		APPLE	200..283	CDD:128519
		APPLE	291..375	CDD:128519	1/7 (14%)
		Tryp_SPc	389..619	CDD:238113	69/248 (28%)
CG1304	NP_608418.1	Tryp_SPc	32..256	CDD:238113	71/250 (28%)