Protein Alignment F11 and Hayan

DIOPT Version :10

• Sequence 1: XP_005262878.1
• Gene: F11 / 2160
• HGNCID: 3529
• Length: 626
• Species: Homo sapiens
• Sequence 2: NP_001097020.1
• Gene: Hayan / 32831
• FlyBaseID: FBgn0030925
• Length: 637
• Species: Drosophila melanogaster
• Alignment Length: 312
• Identity: 87/312 - (27%)
• Similarity: 136/312 - (43%)
• Gaps: 76/312 - (24%)

Human   334 PAQASCNEGNRGKCYLKLSSNGSPTKILHGRGGISGYTLRLCKMDNECTTKIKPRIVGGTASVRG 398
            |:.|:|.         |:.|.|.|..:                           .|:.|....||
  Fly   366 PSVAACE---------KIRSGGKPLTV---------------------------HILDGERVDRG 394

Human   399 EWPWQVTL-HTTSPTQRHLCGGSIIGNQWILTAAHCFYGVES-PKILRVYSGILNQSEIKEDTSF 461
            .:|....: :.:..:....||||:|.::::||||||....:| |..:|:  |.||....:.....
  Fly   395 VYPHMAAIAYNSFGSAAFRCGGSLIASRFVLTAAHCVNSDDSTPSFVRL--GALNIENPEPGYQD 457

Human   462 FGVQEIIIHDQYKMAESGYDIALLKLETTVNYTDSQRPICLPSKGDRNVIYTD---------CWV 517
            ..|.::.||..|..:...||||:|:|......:|..||.||         |||         .:|
  Fly   458 INVIDVQIHPDYSGSSKYYDIAILQLAEDAKESDVIRPACL---------YTDRSDPPANYKYFV 513

Human   518 TGWGYRKLRDK-IQNTLQKAKIPLVTNEECQKRY-----------RGHKITHKMICAGYREGGKD 570
            .|||...:.:: :...|.:|.:.||..:||...:           ||  :....:||..:...||
  Fly   514 AGWGVMNVTNRAVSKILLRAALDLVPADECNASFAEQPSANRTLRRG--VIASQLCAADKNQRKD 576

Human   571 ACKGDSGGPLSCKHNEV---WHLVGITSWGEGCAQRERPGVYTNVVEYVDWI 619
            ||:|||||||..:.::|   :.:||:.|.|.|||.: .||:||.|..::|:|
  Fly   577 ACQGDSGGPLILEIDDVDGTYSIVGVISSGFGCATK-TPGLYTRVSSFLDYI 627

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
F11	XP_005262878.1	APPLE	20..103	CDD:128519
		APPLE	110..193	CDD:128519
		APPLE	200..283	CDD:128519
		APPLE	291..375	CDD:128519	7/40 (18%)
		Tryp_SPc	389..619	CDD:238113	79/255 (31%)
Hayan	NP_001097020.1	CLIP	32..80	CDD:197829
		Tryp_SPc	385..630	CDD:238113	80/257 (31%)