Protein Alignment F11 and CG32260

DIOPT Version :10

• Sequence 1: XP_005262878.1
• Gene: F11 / 2160
• HGNCID: 3529
• Length: 626
• Species: Homo sapiens
• Sequence 2: NP_728942.1
• Gene: CG32260 / 317943
• FlyBaseID: FBgn0052260
• Length: 575
• Species: Drosophila melanogaster
• Alignment Length: 270
• Identity: 82/270 - (30%)
• Similarity: 134/270 - (49%)
• Gaps: 36/270 - (13%)

Human   366 GISGYTLRLCKMDNECTTKIKPRIVGGTASVRGEWPWQVTLHTTSPTQRH----LCGGSIIGNQW 426
            ||||.|              ..|:|||..:.:|.:||...|.......|:    |||||:|.:::
  Fly   319 GISGAT--------------SNRVVGGMEARKGAYPWIAALGYFEENNRNALKFLCGGSLIHSRY 369

Human   427 ILTAAHCFYGVESPKILRVYSGILNQSEIKEDTSF-FGVQEIIIHDQYKMAESGYDIALLKLETT 490
            ::|:|||.    :|.:..|..|..:.|:..|..:. ..::..::|:.:.:.....||||::|...
  Fly   370 VITSAHCI----NPMLTLVRLGAHDLSQPAESGAMDLRIRRTVVHEHFDLNSISNDIALIELNVV 430

Human   491 VNYTDSQRPICLPSKG---DRNVIYTDCWVTGWGYRKLRDKIQNTLQKAKIPLVTNEECQKRYRG 552
            .....:..|||||...   .::.:..:.:|.|||..|.:......|:.|::|:|:...|::.|:.
  Fly   431 GALPGNISPICLPEAAKFMQQDFVGMNPFVAGWGAVKHQGVTSQVLRDAQVPIVSRHSCEQSYKS 495

Human   553 ----HKITHKMICAGYREGGKDACKGDSGGPLSCKHNE----VWHLVGITSWGEGCAQRERPGVY 609
                .:.:.|::|||  ....|||:|||||||.....|    .::|:|:.|:|..||:...||||
  Fly   496 IFQFVQFSDKVLCAG--SSSVDACQGDSGGPLMMPQLEGNVYRFYLLGLVSFGYECARPNFPGVY 558

Human   610 TNVVEYVDWI 619
            |.|..||.||
  Fly   559 TRVASYVPWI 568

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
F11	XP_005262878.1	APPLE	20..103	CDD:128519
		APPLE	110..193	CDD:128519
		APPLE	200..283	CDD:128519
		APPLE	291..375	CDD:128519	5/8 (63%)
		Tryp_SPc	389..619	CDD:238113	74/245 (30%)
CG32260	NP_728942.1	CLIP	194..244	CDD:463440
		Tryp_SPc	328..571	CDD:238113	76/247 (31%)