Protein Alignment F11 and Sp212

DIOPT Version :10

• Sequence 1: XP_005262878.1
• Gene: F11 / 2160
• HGNCID: 3529
• Length: 626
• Species: Homo sapiens
• Sequence 2: NP_996209.2
• Gene: Sp212 / 2768666
• FlyBaseID: FBgn0053329
• Length: 516
• Species: Drosophila melanogaster
• Alignment Length: 509
• Identity: 118/509 - (23%)
• Similarity: 193/509 - (37%)
• Gaps: 115/509 - (22%)

Human   152 ATRQFPSLEHRNICLLKHTQTGTP--TRITKLDKVVSGFSLKSCALS---------NLACIRDI- 204
            |.||........|.:..::..|.|  ||::..::::       |:.|         |.....||
  Fly    81 AVRQLTGSAKFRIAVRPNSSNGLPKLTRLSYNEQIL-------CSASEYRPPNSFFNRFYELDIS 138

Human   205 -----FPNTVF-------ADSNIDSVMAPDAFVCGRICTHHPGCLFFTFFSQEWPKESQRNLCLL 257
                 ||::||       .|.|:.:|..|         |...|...:..|:|.|...|.|:..::
  Fly   139 GSLASFPSSVFNPFTRDGLDVNVQTVFYP---------TSSRGNDIWRGFTQPWTTVSNRSPAVV 194

Human   258 KTSESGLPSTRIKKSKALSGFSLQSCRHSIPVFCHSSFYHDTDFLGEELDIVAAKSHEACQKLCT 322
            ..:.:   .|.|..::.:.         |:|:                                |
  Fly   195 TPAPT---PTEIFWNQPVP---------SVPI--------------------------------T 215

Human   323 NAVRCQFFTYTPAQASCNEG--NRGKCYLKLSSNGSPTKILHGRGGISGYTLRLCKMDNECTTKI 385
            .|......|.:||.|.....  ......:.:.....|.:....|..||..   :|..:...|
  Fly   216 FAPPVPTITSSPAPAPPPPPPLPTPPAVVTVPPATPPPQRFDPRSQISSV---VCGREGSTT--- 274

Human   386 KPRIVGGTASVRGEWPW-QVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFYGVESPKILRVYSGI 449
             |.||.|....||::|| ....|.........|.||:|.:..:::||||.:.:...::: |..|.
  Fly   275 -PFIVRGNEFPRGQYPWLSAVYHKEVRALAFKCRGSLISSSIVISAAHCVHRMTEDRVV-VGLGR 337

Human   450 LNQSEIKED-TSFFGVQEIIIHDQYK-MAESGYDIALLKLETTVNYTDSQRPICLPSKGDRNVIY 512
            .:..:..|| .....|..::.|..|. .:.|..||||:.:|..|.:.|...|||:.:......:.
  Fly   338 YDLDDYGEDGAEMRNVMRLLWHPDYNTRSYSDADIALITIERPVTFNDIIAPICMWTVEASRTVS 402

Human   513 TDCWVTGWGYRKLRDKIQNTLQKAKIPLVTNEE------CQKRYRGHKITHKMICAGYREGGKDA 571
            |..::.|||    ||:..:   :.:.|.|...|      |...:||..:|.:.:|||.|: |...
  Fly   403 TTGFIAGWG----RDEDSS---RTQYPRVVEAEIASPTVCASTWRGTMVTERSLCAGNRD-GSGP 459

Human   572 CKGDSGGPLSCKHNEVWHLVGITSWGE----GCAQRERPGVYTNVVEYVDWILE 621
            |.|||||.|..|..:.|.|.||.|.||    |..|..:..:|.::.::::||.|
  Fly   460 CVGDSGGGLMVKQGDRWLLRGIVSAGERGPAGTCQLNQYVLYCDLSKHINWISE 513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
F11	XP_005262878.1	APPLE	20..103	CDD:128519
		APPLE	110..193	CDD:128519	8/42 (19%)
		APPLE	200..283	CDD:128519	19/95 (20%)
		APPLE	291..375	CDD:128519	10/85 (12%)
		Tryp_SPc	389..619	CDD:238113	70/242 (29%)
Sp212	NP_996209.2	GD_N	23..127	CDD:464985	10/52 (19%)
		Tryp_SPc	277..514	CDD:238113	73/246 (30%)