Protein Alignment F11 and CG30088

DIOPT Version :10

• Sequence 1: XP_005262878.1
• Gene: F11 / 2160
• HGNCID: 3529
• Length: 626
• Species: Homo sapiens
• Sequence 2: NP_725488.3
• Gene: CG30088 / 246447
• FlyBaseID: FBgn0050088
• Length: 281
• Species: Drosophila melanogaster
• Alignment Length: 270
• Identity: 82/270 - (30%)
• Similarity: 124/270 - (45%)
• Gaps: 41/270 - (15%)

Human   368 SGYTLRLCKMDNECTTKIKPRIVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAH 432
            :.:.:..|.:..|  :.:..|||.|..::....|:...|:.:|...   |||:||.:::||||||
  Fly    26 ANFLIPSCGVSYE--SNVATRIVRGKEAMLKSAPFMAYLYYSSEIH---CGGTIISSRYILTAAH 85

Human   433 CFYGVESPKILRVYSGI-LNQSEIKEDTSFFGVQ--------EIIIHDQYKMAES--GYDIALLK 486
            |         :|.|..: |.:.:|..:....|..        :|::..:||..:.  ..||||||
  Fly    86 C---------MRPYLKVRLGEHDITRNPDCQGGSCSPPAEEFDIVLATKYKRFDRFLANDIALLK 141

Human   487 LETTVNYTDSQRPICL---PSKGDRNVIYTDCWVTGWGYRKLRDKIQNTLQKAKIPLVTNEECQK 548
            |...:.:....:||||   |:... ||  .:....|||..:.... .|.||...:....|..| :
  Fly   142 LSRNIRFNVHIQPICLILNPAAAP-NV--HEFQAFGWGQTETNHS-ANVLQTTVLTRYDNRHC-R 201

Human   549 RYRGHKITHKMICAGYREGGKDACKGDSGGPLSCK--HNEVWHL--VGITSWGEGCAQRERPGVY 609
            ......||...:|.|::  |.|.|.|||||||..|  ::.||..  :||.|:|:...|  .||||
  Fly   202 SVLSMPITINQLCVGFQ--GSDTCSGDSGGPLVTKVNYDGVWRYLQLGIVSFGDDKCQ--SPGVY 262

Human   610 TNVVEYVDWI 619
            |.|..|:.||
  Fly   263 TYVPNYIRWI 272

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
F11	XP_005262878.1	APPLE	20..103	CDD:128519
		APPLE	110..193	CDD:128519
		APPLE	200..283	CDD:128519
		APPLE	291..375	CDD:128519	0/6 (0%)
		Tryp_SPc	389..619	CDD:238113	77/247 (31%)
CG30088	NP_725488.3	Tryp_SPc	45..273	CDD:238113	79/249 (32%)