Protein Alignment F10 and CG31219

DIOPT Version :10

• Sequence 1: NP_000495.1
• Gene: F10 / 2159
• HGNCID: 3528
• Length: 488
• Species: Homo sapiens
• Sequence 2: NP_001097837.1
• Gene: CG31219 / 42344
• FlyBaseID: FBgn0051219
• Length: 345
• Species: Drosophila melanogaster
• Alignment Length: 272
• Identity: 85/272 - (31%)
• Similarity: 136/272 - (50%)
• Gaps: 63/272 - (23%)

Human   234 RIVGGQECKDGECPWQALLI-----NEENEGFCGGTILSEFYILTAAHCLYQAKR----FKVRVG 289
            |:|||.|.:....||.|:|:     ..|...||.|::::..|:||:|||:....|    ..||:|
  Fly    88 RMVGGSEARPNGYPWMAMLLYLNTTTLEILPFCAGSLINNRYVLTSAHCVNGIPRDLSLKSVRLG 152

Human   290 DR----------NTEQEEGGEAVHEVEV----VIKHNRF---TKETYDFDIAVLRLKTPITFRMN 337
            :.          :...::...|:..:|:    :|.|..|   :....::|||:||||.|:.:|..
  Fly   153 EHDITYDPAYNPDCRDQDNQCALPNLEIKLEKIIVHGLFSSISNRNIEYDIALLRLKMPVRYRTG 217

Human   338 VAPACLPERD-WAESTLMTQKTGIVSGFGRTHEKGR------------QSTRLKMLEVPYVDRNS 389
            :.|.|:|:.. :|:|.|.      ::|:|:|:| |:            :|..:..|..||:|.|
  Fly   218 IMPICIPKHGFFAKSKLE------IAGWGKTNE-GQFSQVLMHGFIRERSIAVCALRFPYLDLN- 274

Human   390 CKLSSSFIITQNM-FCA-GYDTKQEDACQGDSGGP-HVTRFKDTYFVTGIVSWG-EGCARKGKYG 450
                      |:: .|| |||  ..|.|||||||| .||....:.::.||.::| :.|.:.|..|
  Fly   275 ----------QSLQICAGGYD--GVDTCQGDSGGPLMVTMDNSSVYLAGITTYGSKNCGQIGIPG 327

Human   451 IYTKVTAFLKWI 462
            |||:.:|||.||
  Fly   328 IYTRTSAFLPWI 339

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
F10	NP_000495.1	GLA	25..85	CDD:214503
		EGF_CA	86..122	CDD:238011
		FXa_inhibition	129..164	CDD:464251
		O-glycosylated at one site	183..203
		Tryp_SPc	235..464	CDD:238113	84/271 (31%)
		O-glycosylated at one site	476..485
CG31219	NP_001097837.1	Tryp_SPc	88..339	CDD:214473	83/270 (31%)