Protein Alignment F10 and CG5255

DIOPT Version :10

• Sequence 1: NP_000495.1
• Gene: F10 / 2159
• HGNCID: 3528
• Length: 488
• Species: Homo sapiens
• Sequence 2: NP_650604.1
• Gene: CG5255 / 42073
• FlyBaseID: FBgn0038485
• Length: 273
• Species: Drosophila melanogaster
• Alignment Length: 259
• Identity: 80/259 - (30%)
• Similarity: 119/259 - (45%)
• Gaps: 33/259 - (12%)

Human   234 RIVGGQECKDGECPWQALLINEENEGF------CGGTILSEFYILTAAHCL--YQAKRFKVRVGD 290
            |||||:|...|..|:|..|     :|.      |||.|:.|.:|:|||||.  .||..|:|..|.
  Fly    29 RIVGGEEAAAGLAPYQISL-----QGIGSGAHSCGGAIIDERWIITAAHCTRGRQATAFRVLTGT 88

Human   291 RNTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAESTLMT 355
            ::..|  .|...:..:.:::|:.:....|..|||:|.|...|.|.....|.   |.|  ...|:.
  Fly    89 QDLHQ--NGSKYYYPDRIVEHSNYAPRKYRNDIALLHLNESIVFDNATQPV---ELD--HEALVP 146

Human   356 QKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLS--SSFIITQNMFCAGYDTKQEDACQGD 418
            ....:::|:|.....|....||:.|||.||....|:.:  :|..:.....|. ::.|...||.||
  Fly   147 GSRLLLTGWGTLSLGGDVPARLQSLEVNYVPFEQCRAAHDNSTRVDIGHVCT-FNDKGRGACHGD 210

Human   419 SGGPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWIDRSMKTRGLPKAKSHAPEVI 482
            ||||.|...|    :..:|:||..|| ||    |....|.:.:....::|. |..:|:.:.|.|
  Fly   211 SGGPLVHNGK----LVALVNWGLPCA-KG----YPDAHASISYYHDFIRTH-LSLSKTDSSEDI 264

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
F10	NP_000495.1	GLA	25..85	CDD:214503
		EGF_CA	86..122	CDD:238011
		FXa_inhibition	129..164	CDD:464251
		O-glycosylated at one site	183..203
		Tryp_SPc	235..464	CDD:238113	74/238 (31%)
		O-glycosylated at one site	476..485		2/7 (29%)
CG5255	NP_650604.1	Tryp_SPc	29..249	CDD:214473	75/241 (31%)