Protein Alignment F10 and CG12951

DIOPT Version :10

• Sequence 1: NP_000495.1
• Gene: F10 / 2159
• HGNCID: 3528
• Length: 488
• Species: Homo sapiens
• Sequence 2: NP_649880.1
• Gene: CG12951 / 41110
• FlyBaseID: FBgn0037677
• Length: 265
• Species: Drosophila melanogaster
• Alignment Length: 243
• Identity: 66/243 - (27%)
• Similarity: 111/243 - (45%)
• Gaps: 22/243 - (9%)

Human   231 NLTRIVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCL--YQAKRFKVRVGDRNT 293
            :::|:|.|.:....:.|:...|.:.:....|||:|:|:.:::|||||.  ..|....::.|..|.
  Fly    26 SISRVVNGTDSSVLKYPFVVSLRSYDGSHSCGGSIISKHFVMTAAHCTNGRPADTLSIQFGVTNI 90

Human   294 EQEEGGEAVHEVEVVIKHNRF--TKETYDFDIAVLRLKTPITF-RMNVAPACLPERDWAESTLMT 355
            ...  |..|..::.:|:|..|  |::..: ||::|.::.|..| .::|||..||...:|......
  Fly    91 SAM--GPNVVGIKKIIQHEDFDPTRQNAN-DISLLMVEEPFEFDGVSVAPVELPALAFAVPQSDA 152

Human   356 QKTGIVSGFGRTHEKGR-----QSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTKQEDAC 415
            ...|::.|:|.....|.     |...||:    |.|.......:.....:...|.|.|...:..|
  Fly   153 GVEGVLIGWGLNDTYGSVQDTLQEVSLKI----YSDEECTSRHNGQTDPKYHICGGVDEGGKGQC 213

Human   416 QGDSGGPHVTRFKDTYFVTGIVSWG-EGCARKGKYGIYTKVTAFLKWI 462
            .||||||.:...:.    .|||||. :.|......|:|.||:.::.||
  Fly   214 SGDSGGPLIYNGQQ----VGIVSWSIKPCTVAPYPGVYCKVSQYVDWI 257

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
F10	NP_000495.1	GLA	25..85	CDD:214503
		EGF_CA	86..122	CDD:238011
		FXa_inhibition	129..164	CDD:464251
		O-glycosylated at one site	183..203
		Tryp_SPc	235..464	CDD:238113	65/239 (27%)
		O-glycosylated at one site	476..485
CG12951	NP_649880.1	Tryp_SPc	30..260	CDD:238113	65/239 (27%)