Protein Alignment F10 and CG32374

DIOPT Version :10

• Sequence 1: NP_000495.1
• Gene: F10 / 2159
• HGNCID: 3528
• Length: 488
• Species: Homo sapiens
• Sequence 2: NP_729270.1
• Gene: CG32374 / 38848
• FlyBaseID: FBgn0052374
• Length: 299
• Species: Drosophila melanogaster
• Alignment Length: 270
• Identity: 89/270 - (32%)
• Similarity: 125/270 - (46%)
• Gaps: 27/270 - (10%)

Human   210 PTENPFDLLDFN-QTQP-----ERGDNNLTRIVGGQECKDGECPWQALLINEENEGFCGGTILSE 268
            |...|...|..| .|.|     |..|...||||.|::.|....|:|..| :..|...||..||:.
  Fly    43 PRIKPQTFLPGNISTNPAINALEAQDYLPTRIVNGKKIKCSRAPYQCAL-HYNNYFICGCVILNR 106

Human   269 FYILTAAHC-LYQAKRFKVRVGDRNTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPI 332
            .:||||.|| :....|:.||.|  :|:|..||:..| |:..:.|..:::.|...|:.:::||||:
  Fly   107 RWILTAQHCKIGNPGRYTVRAG--STQQRRGGQLRH-VQKTVCHPNYSEYTMKNDLCMMKLKTPL 168

Human   333 TFRMNVAPACLPERDWAESTLMTQKTGIVSGFGRTHEKGRQSTR-LKMLEVPYVDRNSCK---LS 393
            .....|....||    :..|....|..:.||:|.|....:...| |:.:.|..|.|..|:   ..
  Fly   169 NVGRCVQKVKLP----STRTKRFPKCYLASGWGLTSANAQNVQRYLRGVIVCKVSRAKCQQDYRG 229

Human   394 SSFIITQNMFCAGYDTKQEDACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKY-GIYTKVTA 457
            :...|.:.|.||  ..|..|.|.||||||.|    ....:.||.|:|.||| ..|| |:|..|..
  Fly   230 TGIKIYKQMICA--KRKNRDTCSGDSGGPLV----HNGVLYGITSFGIGCA-SAKYPGVYVNVLQ 287

Human   458 FLKWIDRSMK 467
            :.:||.:..|
  Fly   288 YTRWIKKVAK 297

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
F10	NP_000495.1	GLA	25..85	CDD:214503
		EGF_CA	86..122	CDD:238011
		FXa_inhibition	129..164	CDD:464251
		O-glycosylated at one site	183..203
		Tryp_SPc	235..464	CDD:238113	78/234 (33%)
		O-glycosylated at one site	476..485
CG32374	NP_729270.1	Tryp_SPc	73..292	CDD:214473	77/233 (33%)