Protein Alignment F10 and CG6462

DIOPT Version :10

• Sequence 1: NP_000495.1
• Gene: F10 / 2159
• HGNCID: 3528
• Length: 488
• Species: Homo sapiens
• Sequence 2: NP_648011.1
• Gene: CG6462 / 38681
• FlyBaseID: FBgn0035663
• Length: 319
• Species: Drosophila melanogaster
• Alignment Length: 262
• Identity: 76/262 - (29%)
• Similarity: 126/262 - (48%)
• Gaps: 32/262 - (12%)

Human   218 LDFNQTQPERGDNNLTRIVGGQECKDGECPWQALLINEENEG---FCGGTILSEFYILTAAHCLY 279
            ::.|||...|     |||.||:....|..|:|..|:.:.:..   .|||::::..::|||||||.
  Fly    65 MEGNQTAAVR-----TRIAGGELATRGMFPYQVGLVIQLSGADLVKCGGSLITLQFVLTAAHCLT 124

Human   280 QAKRFKVRVGDRNTEQEEGGEAVHEVEVVIKHNRFTKETY-DF-------DIAVLRLKTPITFRM 336
            .|...|:..|  .|...:..::|.|::|.  |..|.  .| |:       |:|::||...:....
  Fly   125 DAIAAKIYTG--ATVFADVEDSVEELQVT--HRDFI--IYPDYLGFGGYSDLALIRLPRKVRTSE 183

Human   337 NVAPACLPERDWAESTLMTQKTGIVSGFGRTHEKGRQSTR-LKMLEVPYVDRNSCKLSSSF---I 397
            .|.|..| ..::.....:..|...:||:|...:...:.|| |:.|:...:|:..|  ...|   :
  Fly   184 QVQPIEL-AGEFMHQNFLVGKVVTLSGWGYLGDSTDKRTRLLQYLDAEVIDQERC--ICYFLPGL 245

Human   398 ITQNMFCAGYDTKQEDACQGDSGGPHVTRFKDTYFVTGIVSWG--EGCARKGKYGIYTKVTAFLK 460
            ::|........:....||.||||||.|..:::..::.|:.|:|  ||| ..|...:||::||:|.
  Fly   246 VSQRRHLCTDGSNGRGACNGDSGGPVVYHWRNVSYLIGVTSFGSAEGC-EVGGPTVYTRITAYLP 309

Human   461 WI 462
            ||
  Fly   310 WI 311

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
F10	NP_000495.1	GLA	25..85	CDD:214503
		EGF_CA	86..122	CDD:238011
		FXa_inhibition	129..164	CDD:464251
		O-glycosylated at one site	183..203
		Tryp_SPc	235..464	CDD:238113	70/245 (29%)
		O-glycosylated at one site	476..485
CG6462	NP_648011.1	Tryp_SPc	77..314	CDD:238113	70/245 (29%)