Protein Alignment F10 and CG3650

DIOPT Version :10

• Sequence 1: NP_000495.1
• Gene: F10 / 2159
• HGNCID: 3528
• Length: 488
• Species: Homo sapiens
• Sequence 2: NP_611971.1
• Gene: CG3650 / 37974
• FlyBaseID: FBgn0035070
• Length: 249
• Species: Drosophila melanogaster
• Alignment Length: 280
• Identity: 84/280 - (30%)
• Similarity: 128/280 - (45%)
• Gaps: 45/280 - (16%)

Human   200 WKPYDAADLDPTENPFDLLDFNQTQPERGDNNLTRIVGGQ----ECKDGECPWQALLINEENEG- 259
            |:|.....|  |:....|.. .|.||        |||||.    ....|      .::|...:|
  Fly     2 WRPLFLLQL--TQLLLGLAS-GQIQP--------RIVGGTTTTLSAVGG------FVVNLRYDGT 49

Human   260 -FCGGTILSEFYILTAAHCL--YQAKRFKVRVGDRNTEQEEGGEAVHEVEVVIKHNRFTKETYDF 321
             :|||::::..:::||||||  |||.|..|:.|.....|   ...|..|......|.|:..:.::
  Fly    50 FYCGGSLVTSSHVVTAAHCLKGYQASRITVQGGVSKLSQ---SGVVRRVARYFIPNGFSSSSLNW 111

Human   322 DIAVLRLKTPIT-FRMNVAPACLPERDWAESTLMTQKTGIVSGFGRT-HEKGRQSTRLKMLEVPY 384
            |:.|:||::.:| ..:...|.|  :..|.....|.     |||:|.| :.....|.:|:.:.:..
  Fly   112 DVGVIRLQSALTGSGITTIPLC--QVQWNPGNYMR-----VSGWGTTRYGNSSPSNQLRTVRIQL 169

Human   385 VDRNSCK--LSSSFIITQNMFCAGYDTKQEDACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKG 447
            :.:..|:  ......:|.:.|||  .|..:|:|.|||||..:  ||:.  :.||||||.|||...
  Fly   170 IRKKVCQRAYQGRDTLTASTFCA--RTGGKDSCSGDSGGGVI--FKNQ--LCGIVSWGLGCANAQ 228

Human   448 KYGIYTKVTAFLKWIDRSMK 467
            ..|:||.|.....:|.||:|
  Fly   229 YPGVYTSVHRVRSFILRSIK 248

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
F10	NP_000495.1	GLA	25..85	CDD:214503
		EGF_CA	86..122	CDD:238011
		FXa_inhibition	129..164	CDD:464251
		O-glycosylated at one site	183..203		1/2 (50%)
		Tryp_SPc	235..464	CDD:238113	72/240 (30%)
		O-glycosylated at one site	476..485
CG3650	NP_611971.1	Tryp_SPc	25..243	CDD:214473	72/239 (30%)