Protein Alignment F10 and CG32270

DIOPT Version :10

• Sequence 1: NP_000495.1
• Gene: F10 / 2159
• HGNCID: 3528
• Length: 488
• Species: Homo sapiens
• Sequence 2: NP_728837.1
• Gene: CG32270 / 3772375
• FlyBaseID: FBgn0052270
• Length: 259
• Species: Drosophila melanogaster
• Alignment Length: 246
• Identity: 75/246 - (30%)
• Similarity: 114/246 - (46%)
• Gaps: 41/246 - (16%)

Human   234 RIVGGQECKDGECPW-QALLINEENEG--FCGGTILSEFYILTAAHCLYQA--KRFKVRVG---- 289
            |||||....    .| |..::|....|  .|||::::...:|||||||...  ..|.||.|
  Fly    30 RIVGGHPSD----VWHQPHMVNIRRRGNFECGGSLVTPRCVLTAAHCLNDGNPSDFVVRGGVTYL 90

Human   290 --DRNTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVA-PACLPERDWAES 351
              .||:..         |..::..:.:::.|.|.|:|:|:||.|:  :.::| |..|..|.....
  Fly    91 SDMRNSRY---------VRKILMPSAYSRTTLDHDVALLQLKQPL--QASIAKPISLAVRSPRPG 144

Human   352 TLMTQKTGIVSGFGRTHEKGRQ-STRLKMLEVPYVDRNSCK-LSSSF-IITQNMFCAGYDTKQED 413
            :.:.     |||:|.|...... ..:|:.:.|..:.:..|: |...: .||.:||||.. ...:|
  Fly   145 SFVR-----VSGWGLTDSSSTSLPNQLQSVHVQVMPQRECRDLYRGYRNITSSMFCASV-PGLKD 203

Human   414 ACQGDSGGPHVTRFKDTYFVTGIVSWGEG--CARKGKYGIYTKVTAFLKWI 462
            ||.||||||.|   .....:.|:||||..  ||.:...|:|:.|:....||
  Fly   204 ACAGDSGGPVV---NSNGILVGVVSWGRAHRCAARDSPGVYSDVSYLSDWI 251

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
F10	NP_000495.1	GLA	25..85	CDD:214503
		EGF_CA	86..122	CDD:238011
		FXa_inhibition	129..164	CDD:464251
		O-glycosylated at one site	183..203
		Tryp_SPc	235..464	CDD:238113	74/245 (30%)
		O-glycosylated at one site	476..485
CG32270	NP_728837.1	Tryp_SPc	30..251	CDD:214473	73/244 (30%)