Protein Alignment F10 and CG30414

DIOPT Version :10

• Sequence 1: NP_000495.1
• Gene: F10 / 2159
• HGNCID: 3528
• Length: 488
• Species: Homo sapiens
• Sequence 2: NP_611789.2
• Gene: CG30414 / 37705
• FlyBaseID: FBgn0050414
• Length: 305
• Species: Drosophila melanogaster
• Alignment Length: 288
• Identity: 78/288 - (27%)
• Similarity: 123/288 - (42%)
• Gaps: 58/288 - (20%)

Human   214 PFDLLDFN--QTQPERGDNNLTRIVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAH 276
            |..|||.:  .|:||    .:..|.||.:......||...::.|:   .|||::::..::|||||
  Fly    22 PGHLLDSSCGTTKPE----FIPMITGGADAGLFSNPWMVKVLGEK---LCGGSLITSRFVLTAAH 79

Human   277 CLYQAKRFKVRVGDRNTEQEEGGEAVHEVEVVIKHNRFTKETYDF-------------------- 321
            |:. :...:||:|:..| :..|.:....|....|..|.....||.
  Fly    80 CIV-STHMRVRLGEYKT-RFPGKDCSRCVPKSYKLRRIRLGEYDTRFPGKDCCVPKSYELAVDRK 142

Human   322 ------------DIAVLRLKTPITFRMNVAPAC-LPERDWAESTLMTQKTGIVSGFGRTHEKGRQ 373
                        ||.:||:|:.:.:...|.|.| |.|...|||.:..     ::|:|.|:: |..
  Fly   143 ILHADYNLNLDNDIGLLRMKSFVQYSDYVRPICLLVEGHMAESPIFN-----ITGWGVTND-GTP 201

Human   374 STRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTKQEDACQGDSGGPHVTR--FKDTY--FVT 434
            |.||:...|...|.:.|:...:..:.::..||.  ....|||.||||||...:  |..::  |..
  Fly   202 SRRLQRATVYNTDLHFCRSKFTKQVDESQICAA--GTNSDACHGDSGGPLSAQVPFAGSWLTFQY 264

Human   435 GIVSWGEGCARKGKYGIYTKVTAFLKWI 462
            |:||:|.....  .:.:||.||....||
  Fly   265 GLVSYGSAACH--SFSVYTNVTHHRDWI 290

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
F10	NP_000495.1	GLA	25..85	CDD:214503
		EGF_CA	86..122	CDD:238011
		FXa_inhibition	129..164	CDD:464251
		O-glycosylated at one site	183..203
		Tryp_SPc	235..464	CDD:238113	71/265 (27%)
		O-glycosylated at one site	476..485
CG30414	NP_611789.2	Tryp_SPc	41..290	CDD:238113	69/263 (26%)