Protein Alignment F10 and Phae2

DIOPT Version :10

• Sequence 1: NP_000495.1
• Gene: F10 / 2159
• HGNCID: 3528
• Length: 488
• Species: Homo sapiens
• Sequence 2: NP_609551.2
• Gene: Phae2 / 34638
• FlyBaseID: FBgn0263235
• Length: 265
• Species: Drosophila melanogaster
• Alignment Length: 267
• Identity: 68/267 - (25%)
• Similarity: 113/267 - (42%)
• Gaps: 52/267 - (19%)

Human   224 QPERGDNNLTRIVGGQECKDGECPWQALLINEENEG--FCGGTILSEFYILTAAHCLYQAKRFKV 286
            |||      .|:|||:.......|:   :::.:..|  :|...|::..:::||||||  |.|.:|
  Fly    27 QPE------GRVVGGKAAAANSAPY---IVSMQYGGTHYCAANIINSNWLVTAAHCL--ANRNQV 80

Human   287 R-----------VGDRNTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAP 340
            .           .|..:|.|:      .::...:.::.:|..|..:||.::...|..|:...|||
  Fly    81 LGSTLVAGSIAVAGTASTTQK------RQITHYVINDLYTGGTVPYDIGLIYTPTAFTWTAAVAP 139

Human   341 ACLPERDWAESTLMTQKTGIVSGFG-----RTHEKGRQSTRLKMLEVPYVDRNSCKLS----SSF 396
            ..||...       .:.||....||     :|:......|..:...:|.:..:||..:    ...
  Fly   140 VKLPSSG-------VRPTGKADLFGWGSTSKTNSPSYPKTLQEAKNIPIISLDSCAAALGSKGQD 197

Human   397 IITQNMFCAGYDTKQEDACQGDSGGPHVTRFKDTYFVTGIVSWGE-GCARKGKYGIYTKVTAFLK 460
            :.|.|: |.|..|.....|..|||||.|    ....:.||||||: .|.:.....:|.:|::|:.
  Fly   198 VHTTNL-CTGPLTGGTSFCTSDSGGPLV----QGNVLIGIVSWGKLPCGQPNSPSVYVQVSSFIT 257

Human   461 WIDRSMK 467
            ||..:.|
  Fly   258 WIAANQK 264

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
F10	NP_000495.1	GLA	25..85	CDD:214503
		EGF_CA	86..122	CDD:238011
		FXa_inhibition	129..164	CDD:464251
		O-glycosylated at one site	183..203
		Tryp_SPc	235..464	CDD:238113	63/251 (25%)
		O-glycosylated at one site	476..485
Phae2	NP_609551.2	Tryp_SPc	32..262	CDD:238113	63/252 (25%)