Protein Alignment F10 and CG4271

DIOPT Version :10

• Sequence 1: NP_000495.1
• Gene: F10 / 2159
• HGNCID: 3528
• Length: 488
• Species: Homo sapiens
• Sequence 2: NP_608665.1
• Gene: CG4271 / 33410
• FlyBaseID: FBgn0031409
• Length: 242
• Species: Drosophila melanogaster
• Alignment Length: 264
• Identity: 66/264 - (25%)
• Similarity: 100/264 - (37%)
• Gaps: 75/264 - (28%)

Human   244 GECPWQALLINEENEGF------------------------CGGTILSEFYILTAAHCLYQ--AK 282
            |.| |..:|....:.|.                        |||.::....:||||.|:..  .|
  Fly     4 GSC-WVLILFARSSNGIYNGVEAKFDFWTFLASVWVSGYHECGGAVIDSRIVLTAAQCVKNKPVK 67

Human   283 RFKVRVGDRNTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPI-TFRMNVAPACLPE- 345
            |..||||  ..:...||..:....:|:..|   .:.:|.|||:|.|:.|: :.|:...|....|
  Fly    68 RITVRVG--TPDIYRGGRIIRVTALVVHEN---YKNWDNDIALLWLEKPVLSVRVTKIPLATKEP 127

Human   346 --------RDWA----ESTLMTQK--TGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSF 396
                    ..|.    ||.::|:|  .|:              |:::       .|:.|......
  Fly   128 SENEYPSNAGWGEKLLESYVVTRKLQNGV--------------TKIR-------PRSMCAEELVE 171

Human   397 IITQNMFCAGYDTKQEDACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKW 461
            .:.:.:.||.|  .:.|.|.||.|||.|...|    |.||...|.||.......:||.|..:|:|
  Fly   172 PVGEELLCAFY--TENDICPGDYGGPLVLANK----VVGIAVQGHGCGFAVLPSLYTNVFHYLEW 230

Human   462 IDRS 465
            |:.:
  Fly   231 IEEN 234

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
F10	NP_000495.1	GLA	25..85	CDD:214503
		EGF_CA	86..122	CDD:238011
		FXa_inhibition	129..164	CDD:464251
		O-glycosylated at one site	183..203
		Tryp_SPc	235..464	CDD:238113	66/261 (25%)
		O-glycosylated at one site	476..485
CG4271	NP_608665.1	Tryp_SPc	19..234	CDD:238113	61/246 (25%)