Protein Alignment F10 and CG6048

DIOPT Version :10

• Sequence 1: NP_000495.1
• Gene: F10 / 2159
• HGNCID: 3528
• Length: 488
• Species: Homo sapiens
• Sequence 2: NP_572282.1
• Gene: CG6048 / 31528
• FlyBaseID: FBgn0029827
• Length: 362
• Species: Drosophila melanogaster
• Alignment Length: 282
• Identity: 85/282 - (30%)
• Similarity: 129/282 - (45%)
• Gaps: 48/282 - (17%)

Human   218 LDFNQTQPERGDNNLTRIVGGQECKDGECPWQALLINEENEGF-------CGGTILSEFYILTAA 275
            ||....:| |.:.:..||:.|.|...|....|..:....|:|:       |||:::...::||||
  Fly    30 LDTKAIRP-RFNADPGRIINGTEASLGATRHQVGIRKALNDGYFFGTGHLCGGSLIRPGWVLTAA 93

Human   276 HC-----LYQA-----KRFKVRVGDRNTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLK- 329
            ||     :|..     :.|.|.:|:.:.............|.:::.::|...|||.|||:|.|.
  Fly    94 HCFVDQIIYDGTFVPKEEFIVVMGNLDRYNRTNTLTFTIEERIMQLDKFDLSTYDKDIALLMLNG 158

Human   330 TPITFRMNVAPACL-----PERDWAESTLMTQKTGI---VSGFGRTHEKGRQSTRLKMLEVPYVD 386
            |..|....:.|..|     ||             |:   |:|:|.| |.|..|..|..::||.:.
  Fly   159 TVPTGHPTIRPIALNRFAIPE-------------GVVCQVTGWGNT-EDGYVSDILMTVDVPMIS 209

Human   387 RNSCKLSSSF--IITQNMFCAGY-DTKQEDACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGK 448
            ...|...|..  :|...|.|||| :..::|||.||||||.|.:.:    :.|:||||..||....
  Fly   210 EEHCINDSDLGHLIQPGMICAGYLEVGEKDACAGDSGGPLVCQSE----LAGVVSWGIQCALPRL 270

Human   449 YGIYTKVTAFLKWIDRSMKTRG 470
            .|:||:|:.:..||.::|...|
  Fly   271 PGVYTEVSYYYDWILQNMGENG 292

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
F10	NP_000495.1	GLA	25..85	CDD:214503
		EGF_CA	86..122	CDD:238011
		FXa_inhibition	129..164	CDD:464251
		O-glycosylated at one site	183..203
		Tryp_SPc	235..464	CDD:238113	78/257 (30%)
		O-glycosylated at one site	476..485
CG6048	NP_572282.1	Tryp_SPc	45..284	CDD:214473	77/256 (30%)