Protein Alignment F10 and CG18420

DIOPT Version :10

• Sequence 1: NP_000495.1
• Gene: F10 / 2159
• HGNCID: 3528
• Length: 488
• Species: Homo sapiens
• Sequence 2: NP_995715.1
• Gene: CG18420 / 2768924
• FlyBaseID: FBgn0028866
• Length: 299
• Species: Drosophila melanogaster
• Alignment Length: 264
• Identity: 79/264 - (29%)
• Similarity: 126/264 - (47%)
• Gaps: 22/264 - (8%)

Human   234 RIVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTEQEEG 298
            |||.|:.......||.|.|....|:..||||::|...:||||||........||:|:.| .:.:|
  Fly    42 RIVNGKVAVRNSSPWMAFLHTSSNQFICGGTLISRRLVLTAAHCFIPNTTIVVRLGEYN-RKLKG 105

Human   299 GEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLP-ERDWAESTLMTQKTGIVS 362
            ....|:|....:|..:...|:..|||:|||.:.:.::.|:.|.|:. :..| :..:.:.|....:
  Fly   106 YREEHQVNRTFQHRFYDPNTHANDIALLRLVSNVVYKANIRPICIMWDASW-KHHIDSIKVLTGT 169

Human   363 GFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTKQEDACQGDSGGP--HVT 425
            |:||| |....|:.|:.|::.......|...|   :..|.||||  ....:.|.||:|||  .:.
  Fly   170 GWGRT-ESMHDSSELRTLDISRQPSKMCAFGS---VLSNQFCAG--NWNSNLCIGDTGGPVGAMV 228

Human   426 RFKDTY-FV-TGIVSWGEGCARKGKYGIYTKVTAFLKWIDRSMKT-----RGLPKAK-SHAPEVI 482
            |:::.: || .||....:.|.|.   .::|.|.:.:::|.|...|     |..|..| ...||..
  Fly   229 RYRNAFRFVQVGIAITNKRCQRP---SVFTDVMSHIEFIRRIFLTQNGNDRNQPTPKPDKEPEFD 290

Human   483 TSSP 486
            .::|
  Fly   291 WNNP 294

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
F10	NP_000495.1	GLA	25..85	CDD:214503
		EGF_CA	86..122	CDD:238011
		FXa_inhibition	129..164	CDD:464251
		O-glycosylated at one site	183..203
		Tryp_SPc	235..464	CDD:238113	70/233 (30%)
		O-glycosylated at one site	476..485		2/8 (25%)
CG18420	NP_995715.1	Tryp_SPc	42..264	CDD:214473	70/232 (30%)