Protein Alignment F10 and CG18636

DIOPT Version :10

• Sequence 1: NP_000495.1
• Gene: F10 / 2159
• HGNCID: 3528
• Length: 488
• Species: Homo sapiens
• Sequence 2: NP_995714.2
• Gene: CG18636 / 2768923
• FlyBaseID: FBgn0032551
• Length: 349
• Species: Drosophila melanogaster
• Alignment Length: 275
• Identity: 79/275 - (28%)
• Similarity: 122/275 - (44%)
• Gaps: 36/275 - (13%)

Human   234 RIVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGD-RNTEQEE 297
            ||:.|...|....||...|.:..:...|||:::::..:||||||....:....|:|: ..|..||
  Fly    44 RIINGHTAKYNSSPWMVFLHSTTDMFVCGGSLITDKLVLTAAHCFIANQHLVARLGEYERTRSEE 108

Human   298 ------GGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLP-ERDWA----ES 351
                  .....|.|:...||..:...|:..|||:|||...:.:|.|:.|.|:. :..|.    :.
  Fly   109 CTGYYCNFREEHMVDAGFKHKLYDPNTHANDIAILRLSKSVVYRDNIRPICVVWDHRWRHYLDKI 173

Human   352 TLMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAG-YDTKQEDAC 415
            .|:|     .:|:|:|..:. .|..|:.|::.....:.|.......|..|.|||| :|:   :.|
  Fly   174 DLLT-----ATGWGKTQMES-DSDALQTLDIRRQPPDVCAKFIGQTIAGNQFCAGNWDS---NLC 229

Human   416 QGDSGGP--HVTRFKDT--YFVTGIVSW-GEGCARKGKYGIYTKVTAFLKWIDRSMKTRG----L 471
            .||||||  .|...|:|  :...||.|: ...|.   |..::|.|.:..::|.|..:..|    |
  Fly   230 NGDSGGPLGAVITHKNTQRFVQVGIASYTNRNCQ---KASVFTDVLSHAEFILRVWRMYGKGQTL 291

Human   472 PKAKSHAPEVITSSP 486
            |..|.  |...|..|
  Fly   292 PIPKK--PPTTTRPP 304

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
F10	NP_000495.1	GLA	25..85	CDD:214503
		EGF_CA	86..122	CDD:238011
		FXa_inhibition	129..164	CDD:464251
		O-glycosylated at one site	183..203
		Tryp_SPc	235..464	CDD:238113	70/246 (28%)
		O-glycosylated at one site	476..485		2/8 (25%)
CG18636	NP_995714.2	Tryp_SPc	45..278	CDD:238113	69/244 (28%)