Protein Alignment F10 and CG33225

DIOPT Version :10

• Sequence 1: NP_000495.1
• Gene: F10 / 2159
• HGNCID: 3528
• Length: 488
• Species: Homo sapiens
• Sequence 2: NP_001286682.1
• Gene: CG33225 / 2768860
• FlyBaseID: FBgn0053225
• Length: 307
• Species: Drosophila melanogaster
• Alignment Length: 270
• Identity: 79/270 - (29%)
• Similarity: 122/270 - (45%)
• Gaps: 29/270 - (10%)

Human   221 NQTQPERGDNNLTRIVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFK 285
            |.....|..:.:.|:|||.:......||..:::.|.|. ||.|::::..::||:|.||....: :
  Fly    43 NDCGTTRHPSRIRRVVGGNDADRFANPWMVMVLGENNV-FCSGSLITRLFVLTSASCLLSLPK-Q 105

Human   286 VRVG--DRNTEQEE--GGEAVHEVEVVIKHNRFTKETY-DFDIAVLRLKTPITFRMNVAPACLP- 344
            |.:|  |||....:  ....|.:::..|.|.:|..||. .:|||:|||...::....|.|.||.
  Fly   106 VILGEYDRNCTSADCTSIRQVIDIDQKIIHGQFGLETVKKYDIALLRLAKKVSISDYVRPICLSV 170

Human   345 ERDWAESTLMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDT 409
            :|....|......|    |:|.| |....||.|:.:.:..::|..||......|..:..|.|...
  Fly   171 DRQVGRSVQHFTAT----GWGTT-EWNEPSTILQTVTLSKINRKYCKGRLRQNIDASQLCVGGPR 230

Human   410 KQEDACQGDSGGPHVTRF----------KDTYFVTGIVSWG-EGCARKGKYGIYTKVTAFLKWID 463
            |  |.|.||:|||.....          |...|:.||||:| ..|:   ..|:||.|..::.||.
  Fly   231 K--DTCSGDAGGPLSLTLKIDGDGKWNNKSRAFLIGIVSYGSSSCS---GIGVYTNVEHYMDWIV 290

Human   464 RSMKTRGLPK 473
            |::......|
  Fly   291 RTINKSNTEK 300

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
F10	NP_000495.1	GLA	25..85	CDD:214503
		EGF_CA	86..122	CDD:238011
		FXa_inhibition	129..164	CDD:464251
		O-glycosylated at one site	183..203
		Tryp_SPc	235..464	CDD:238113	74/245 (30%)
		O-glycosylated at one site	476..485
CG33225	NP_001286682.1	Tryp_SPc	56..289	CDD:214473	73/244 (30%)