Protein Alignment F10 and CG33462

DIOPT Version :10

• Sequence 1: NP_000495.1
• Gene: F10 / 2159
• HGNCID: 3528
• Length: 488
• Species: Homo sapiens
• Sequence 2: NP_995844.2
• Gene: CG33462 / 2768841
• FlyBaseID: FBgn0053462
• Length: 300
• Species: Drosophila melanogaster
• Alignment Length: 273
• Identity: 66/273 - (24%)
• Similarity: 110/273 - (40%)
• Gaps: 48/273 - (17%)

Human   234 RIVGGQECKDGEC------------------PWQALLINEENEGF-CGGTILSEFYILTAAHCLY 279
            |:.|.|...:.:|                  ||.|.|  |..:|| |.||:::..::||||||:.
  Fly    17 RVQGFQMLLEEDCGIPHNISERSVNAKLAQNPWMAYL--ETPKGFHCSGTLINHLFVLTAAHCVP 79

Human   280 QAKRFKVRVGDRNTE----------QEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITF 334
            ......||:|:.||:          ||...|  :.|::..:|..:.......||.:|||...:.:
  Fly    80 DDLLITVRLGEYNTKTKVDCDNHLCQEPFQE--YNVDMGFRHRYYNANDQTNDIGMLRLGRRVEY 142

Human   335 RMNVAPACLPERDWAESTL---MTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSF 396
            ..::.|.|:    :|.:..   :.|.|...:...|.......|..|:.:.:....:.:|.....:
  Fly   143 LNHIRPICI----FASNRFQEPIDQLTWFTTTVWRETAANATSKVLRTMNIDRQPKETCSEIYGW 203

Human   397 IITQNMFCAGYDTKQEDACQGDSGGPHVTRF----KDTYFVTGIVSWGEGCARKGKYGIYTKVTA 457
            .:|....|||....|  .|..|||.|.:.:.    .|.|...||.|..:|..:..  ||...:.:
  Fly   204 NMTFEQICAGNTLSQ--LCSTDSGAPQIRKMWHNGSDRYVQLGIASRVKGQCQNS--GILMDLLS 264

Human   458 FLKWIDRSMKTRG 470
            :..||.|.::..|
  Fly   265 YADWIKRVVRQYG 277

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
F10	NP_000495.1	GLA	25..85	CDD:214503
		EGF_CA	86..122	CDD:238011
		FXa_inhibition	129..164	CDD:464251
		O-glycosylated at one site	183..203
		Tryp_SPc	235..464	CDD:238113	63/264 (24%)
		O-glycosylated at one site	476..485
CG33462	NP_995844.2	Tryp_SPc	48..272	CDD:238113	60/235 (26%)