Protein Alignment F10 and CG30288

DIOPT Version :10

• Sequence 1: NP_000495.1
• Gene: F10 / 2159
• HGNCID: 3528
• Length: 488
• Species: Homo sapiens
• Sequence 2: NP_001097398.1
• Gene: CG30288 / 246531
• FlyBaseID: FBgn0050288
• Length: 282
• Species: Drosophila melanogaster
• Alignment Length: 263
• Identity: 71/263 - (26%)
• Similarity: 112/263 - (42%)
• Gaps: 68/263 - (25%)

Human   234 RIVGGQECKDGECPWQA-LLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTEQEE 297
            ||.||::......||.. ::|:  .:..|||::::..::|||.||: ......||:|:.:|
  Fly    42 RIDGGRDAGMESNPWMVRVMIS--GKAVCGGSLITARFVLTAEHCI-SPMYMNVRLGEYDT---- 99

Human   298 GGEAVHEVEVVIKHNRF-------TKETYD-------------FDIAVLRLKTPITFRMNVAPAC 342
                        :|..|       |...|:             :||.:||::..:.|...|.|.|
  Fly   100 ------------RHPIFDCDDFVCTPRAYNVDVDRKIVHSNPGYDIGLLRMQRSVIFSNYVRPIC 152

Human   343 LPERDWAESTLMTQKTGIV----SGFGRTHEKGRQSTRLKMLEVPYVDRNSCK-----LSSSFII 398
            |    ....||......|:    :|:| |:..|.:..||:...:..:.:.||:     |..|:|
  Fly   153 L----ILGKTLGGNPLSILRFNFTGWG-TNSDGEEQDRLQTATLQQLPQWSCERPGRPLDISYI- 211

Human   399 TQNMFCAGYDTKQEDACQGDSGGP--HVTRF--KDTYFVTGIVSWGEGCARKGKYGIYTKVTAFL 459
                 |||  :...|:|:||||||  .:..|  :...|..|:.|  :|.......||||.||.|.
  Fly   212 -----CAG--SYISDSCKGDSGGPLSAIRTFEGQGRVFQFGVAS--QGLRLCSGLGIYTNVTHFT 267

Human   460 KWI 462
            .||
  Fly   268 DWI 270

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
F10	NP_000495.1	GLA	25..85	CDD:214503
		EGF_CA	86..122	CDD:238011
		FXa_inhibition	129..164	CDD:464251
		O-glycosylated at one site	183..203
		Tryp_SPc	235..464	CDD:238113	70/262 (27%)
		O-glycosylated at one site	476..485
CG30288	NP_001097398.1	Tryp_SPc	45..270	CDD:238113	67/258 (26%)