Protein Alignment F10 and CG30187

DIOPT Version :10

• Sequence 1: NP_000495.1
• Gene: F10 / 2159
• HGNCID: 3528
• Length: 488
• Species: Homo sapiens
• Sequence 2: NP_001246475.2
• Gene: CG30187 / 246509
• FlyBaseID: FBgn0050187
• Length: 500
• Species: Drosophila melanogaster
• Alignment Length: 263
• Identity: 67/263 - (25%)
• Similarity: 112/263 - (42%)
• Gaps: 25/263 - (9%)

Human   228 GDNNLTRIVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRN 292
            |.|...:|.||.........|.| .::......||||::.:.::||||||:.......|.:|..|
  Fly    29 GINIALKITGGHNAAFQNSVWMA-AVHNRTHFICGGTLIHKRFVLTAAHCIVDQDVQSVSLGAYN 92

Human   293 TEQEEGGEAVHEVEVVIKHNRF-TKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAESTLMTQ 356
            .......:   :|...:.|:.| .:.:|:.||.:|:|.:.:.|...:.|.|:.......:.:...
  Fly    93 KSDPADRK---DVITAVVHSSFDVRASYENDIGLLKLSSDVIFNALIRPICIVLNKSMANHMRNM 154

Human   357 KTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTKQEDACQGDSGG 421
            :|....|:| |....:.|..|:.:.:.::||..|.:..|...::...|||  ....|.|.|||||
  Fly   155 RTFKAFGWG-TLRGNKTSDILQTIILNHLDREECYMELSVYPSEKQICAG--VPSGDTCGGDSGG 216

Human   422 PHVTRFKDTYFVTGIVSWGE-----GCARKGK-----YGIYTKVTAFLKWIDRSMKTRGLPKAKS 476
            |    ..:..|:.||   |.     |....||     .|:||.:.:|..||..:::...:.....
  Fly   217 P----LTNDVFIQGI---GNREVQFGIISVGKTSCDGQGVYTDLMSFADWIKMTIERLSIEDEPQ 274

Human   477 HAP 479
            .||
  Fly   275 SAP 277

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
F10	NP_000495.1	GLA	25..85	CDD:214503
		EGF_CA	86..122	CDD:238011
		FXa_inhibition	129..164	CDD:464251
		O-glycosylated at one site	183..203
		Tryp_SPc	235..464	CDD:238113	63/239 (26%)
		O-glycosylated at one site	476..485		2/4 (50%)
CG30187	NP_001246475.2	Tryp_SPc	35..260	CDD:214473	61/238 (26%)
		Trypsin	316..>384	CDD:459667