Protein Alignment F10 and Erasp

DIOPT Version :10

• Sequence 1: NP_000495.1
• Gene: F10 / 2159
• HGNCID: 3528
• Length: 488
• Species: Homo sapiens
• Sequence 2: NP_725487.1
• Gene: Erasp / 246448
• FlyBaseID: FBgn0050090
• Length: 291
• Species: Drosophila melanogaster
• Alignment Length: 272
• Identity: 77/272 - (28%)
• Similarity: 138/272 - (50%)
• Gaps: 46/272 - (16%)

Human   234 RIVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGD-RNTEQEE 297
            :|:||::......||.| .|:...:..||||::::.::||||||:.:....|||:|: .:|..|:
  Fly    39 KIIGGRDAIINSNPWMA-YIHSSVKLICGGTLITQRFVLTAAHCVNEGSAVKVRLGEYDDTATED 102

Human   298 GGEAV-------HEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACL----PERDWAES 351
            ....:       |:|::..:|.:|::.....|||:|||...:||:.:::|.|:    .:|:..:|
  Fly   103 CNSKICIPRAEEHDVDMAFRHGKFSEIKNLNDIALLRLAKFVTFKAHISPICIILGTSKRELVDS 167

Human   352 TLMTQKTGIVSGFG--RTHEKGRQSTR--LKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTKQE 412
            .    :..:.:|:|  |||.     ||  |::.::...:.:.|..:...::.||..|||  ....
  Fly   168 I----EWFVATGWGETRTHR-----TRGVLQITQLQRYNSSQCMQALGRLVQQNQICAG--RLGS 221

Human   413 DACQGDSGGP------HVTRFKDTYFVTGIVSWG-EGCARKGKYGIYTKVTAFLKWIDRSMKTRG 470
            |.|.||||||      |:.:.:...|  |:||:| ..|:   ..|:||.|.::..||      ..
  Fly   222 DTCNGDSGGPLFQTVRHMDKMRPVQF--GVVSYGSRECS---GIGVYTDVYSYADWI------AT 275

Human   471 LPKAKSHAPEVI 482
            :.:..:|.|..|
  Fly   276 VVQQNTHVPAPI 287

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
F10	NP_000495.1	GLA	25..85	CDD:214503
		EGF_CA	86..122	CDD:238011
		FXa_inhibition	129..164	CDD:464251
		O-glycosylated at one site	183..203
		Tryp_SPc	235..464	CDD:238113	74/251 (29%)
		O-glycosylated at one site	476..485		3/7 (43%)
Erasp	NP_725487.1	Tryp_SPc	40..276	CDD:238113	74/258 (29%)