Protein Alignment F10 and CG43110

DIOPT Version :10

• Sequence 1: NP_000495.1
• Gene: F10 / 2159
• HGNCID: 3528
• Length: 488
• Species: Homo sapiens
• Sequence 2: NP_001246396.1
• Gene: CG43110 / 12798330
• FlyBaseID: FBgn0262570
• Length: 483
• Species: Drosophila melanogaster
• Alignment Length: 265
• Identity: 79/265 - (29%)
• Similarity: 123/265 - (46%)
• Gaps: 47/265 - (17%)

Human   228 GDNNLTRIVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRN 292
            |...:.:|:.|.........:.|.:.|..:. .|||||:.|.::||.|||......| ||:|..|
  Fly    29 GKTPVPKIISGSNASQQSAQYMAGIFNTTHL-LCGGTIIHEDFVLTVAHCKSTQTLF-VRLGAYN 91

Human   293 ----TEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAESTL 353
                |:|      :..:| .|.|.:::..||..|||:::|:..:.|.:|:.|.|:    ..::||
  Fly    92 INHPTDQ------IRVIE-TIAHPQYSNSTYANDIALVKLERSVIFNLNIQPICI----HLDATL 145

Human   354 MTQ-KTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNS---CKLSSSFIITQNMFCAGYDTKQEDA 414
            ..| :.....|:|||    |.:.:..:|:..:|:|.:   |.|...........||  .|.|.|.
  Fly   146 GKQIRYYNAFGWGRT----RNAEQSDILQRIFVNRTNPMICHLYLGMSPDPKQICA--TTDQGDT 204

Human   415 CQGDSGGPHVTRFK------DTYFVTGIVSWG-EGCARKGKYGIYTKVTAFLKWI--------DR 464
            |.||||||.:::..      ||.|  ||.|:| ..|   ...|:||.|:.:..||        ||
  Fly   205 CAGDSGGPLISKITYQGKNFDTQF--GITSYGTREC---NGVGLYTDVSQYSGWIANIVRSKQDR 264

Human   465 SMKTR 469
            |:.:|
  Fly   265 SVVSR 269

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
F10	NP_000495.1	GLA	25..85	CDD:214503
		EGF_CA	86..122	CDD:238011
		FXa_inhibition	129..164	CDD:464251
		O-glycosylated at one site	183..203
		Tryp_SPc	235..464	CDD:238113	74/251 (29%)
		O-glycosylated at one site	476..485
CG43110	NP_001246396.1	Tryp_SPc	36..257	CDD:238113	74/244 (30%)