Protein Alignment F9 and CG34458

DIOPT Version :10

• Sequence 1: NP_000124.1
• Gene: F9 / 2158
• HGNCID: 3551
• Length: 461
• Species: Homo sapiens
• Sequence 2: NP_001097340.1
• Gene: CG34458 / 5740868
• FlyBaseID: FBgn0085487
• Length: 257
• Species: Drosophila melanogaster
• Alignment Length: 289
• Identity: 87/289 - (30%)
• Similarity: 139/289 - (48%)
• Gaps: 43/289 - (14%)

Human   183 VSQTSKLTRAETVFPDVDYVNSTEAETILDNITQSTQSFNDFTRVVGGEDAKPGQFPWQV--VLN 245
            :|..:.|.:...:...|.:|:|.     :|...:|        |::||:.|.|||||.||  .||
  Fly     1 MSSVNNLVKLSILLLAVTFVHSD-----MDVAEES--------RIIGGQFAAPGQFPHQVSLQLN 52

Human   246 GKVDAFCGGSIVNEKWIVTAAHCV--ETGVKITVVAGEHNIEETEHTEQKRNVIRIIPHHNYNAA 308
            |:  ..||||::::..|||||||.  :...::..:.|.:::  :....|..|:.:.|.|..||.
  Fly    53 GR--HHCGGSLISDTMIVTAAHCTMGQNPGQMKAIVGTNDL--SAGNGQTFNIAQFIIHPRYNP- 112

Human   309 INKYNHDIALLELDEPLVLNSYVTPICIADKEYTNIFLKFGSGY-------VSGWGRVFHKGRSA 366
             ...:.|::|::|..|:.:...|..|.:||.:         |.|       :||:|.:....:..
  Fly   113 -QSQDFDMSLIKLSSPVPMGGAVQTIQLADSD---------SNYAADTMAMISGFGAINQNLQLP 167

Human   367 LVLQYLRVPLVDRATCLRSTKFTIYNNMFCAGFHEGGRDSCQGDSGGPHVTEVEGTSFLTGIISW 431
            ..|::.:|.|..|..|.......:.:.|.|||...|...|||||||||  ..|:|..|  |::||
  Fly   168 NRLKFAQVQLWSRDYCNSQNIPGLTDRMVCAGHPSGQVSSCQGDSGGP--LTVDGKLF--GVVSW 228

Human   432 GEECAMKGKYGIYTKVSRYVNWIKEKTKL 460
            |..|..||:..:||.|....:|||:...:
  Fly   229 GFGCGAKGRPAMYTYVGALRSWIKQNANV 257

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
F9	NP_000124.1	GLA	28..92	CDD:214503
		EGF_CA	93..129	CDD:238011
		FXa_inhibition	134..170	CDD:464251
		Tryp_SPc	227..457	CDD:238113	79/240 (33%)
CG34458	NP_001097340.1	Tryp_SPc	32..254	CDD:238113	79/240 (33%)