Protein Alignment F9 and CG10232

DIOPT Version :10

• Sequence 1: NP_000124.1
• Gene: F9 / 2158
• HGNCID: 3551
• Length: 461
• Species: Homo sapiens
• Sequence 2: NP_651175.4
• Gene: CG10232 / 42800
• FlyBaseID: FBgn0039108
• Length: 509
• Species: Drosophila melanogaster
• Alignment Length: 476
• Identity: 115/476 - (24%)
• Similarity: 183/476 - (38%)
• Gaps: 115/476 - (24%)

Human    40 ILNRPKRYNSGK-LEEFVQGNLERECMEEKCSFEEAREVFENTERTTEFWKQYVD----GDQC-- 97
            :||...::|..| ..:.::..:.:.|..:.......|.|:.|.:|...|..||.:    .|.|
  Fly    92 MLNDCPQFNGRKWTSDILKSIINKICYIDHFQPLVRRRVYVNCQRQEIFPCQYDEICRSRDSCPF 156

Human    98 ------ESNPCLNGGSCKDDINSYECWCPFGFEGKNCELDVTCNIKNGRCEQFCK-------NSA 149
                  ::...|....|  .||:| | || ..|..:|..|..| |:..:|.:...       |..
  Fly   157 LKLKRKKAQNILMSRQC--GINTY-C-CP-KQEFPDCPADEKC-IRLDKCLRIHNTTMEDGANLM 215

Human   150 DNKVVCSCTEGYRLAENQKS---CEP----AVPFPCGRVSVSQTSKLTRAETVFPDVDYVNSTEA 207
            ||:   .|....|..::.|.   |.|    .:|..||           :|..::
  Fly   216 DNR---QCAIDTRRIDSDKRHYICCPEPGNVLPTSCG-----------QAPPLY----------- 255

Human   208 ETILDNITQSTQSFNDFTRVVGGEDAKPGQFPWQVVL---NGKVDAF---CGGSIVNEKWIVTAA 266
                              |:..|..|:|.::||..:|   |.::...   |.||::|:::::|||
  Fly   256 ------------------RMAYGTAARPNEYPWMAMLIYENRRLSTMTNNCSGSLINKRYVLTAA 302

Human   267 HCVETGVKITVV----------AGEHNIEETEHTEQKRNV--------IRIIPHHNYNAAINKYN 313
            |||   ||..:|          .|||:|......:...|.        |.....|......:::.
  Fly   303 HCV---VKDKMVNTDLVLRRVRLGEHDITTNPDCDFTGNCAAPFVEIGIEYFNVHEQYFNTSRFE 364

Human   314 HDIALLELDEPLVLNSYVTPICIADKEYTNIFLKFGSGYVSGWGRVFHKGRSALVLQYLRVPLVD 378
            .||||:.|..|:.....:.|||:....   |.|......::|||...::..|.::|.  .....:
  Fly   365 SDIALVRLQTPVRYTHEILPICVPKDP---IPLHNHPLQIAGWGYTKNREYSQVLLH--NTVYEN 424

Human   379 RATCLRSTKFTIYNNMFCA-GFHEGGRDSCQGDSGGPHV----TEVEGTSFLTGIISWGEECAMK 438
            |..|.....|....:..|| |..  |.|||:||||||.:    .:.:...:|.||:|:|.|....
  Fly   425 RYYCQDKISFFRNESQICASGIR--GEDSCEGDSGGPLMLTLNNDYQDIVYLAGIVSYGSENCGD 487

Human   439 GKYGIYTKVSRYVNWIKEKTK 459
            .|.|:|||...:.:|||...|
  Fly   488 RKPGVYTKTGAFFSWIKANLK 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
F9	NP_000124.1	GLA	28..92	CDD:214503	11/52 (21%)
		EGF_CA	93..129	CDD:238011	11/47 (23%)
		FXa_inhibition	134..170	CDD:464251	9/45 (20%)
		Tryp_SPc	227..457	CDD:238113	73/258 (28%)
CG10232	NP_651175.4	Tryp_SPc	260..506	CDD:238113	73/255 (29%)