Protein Alignment F9 and CG4613

DIOPT Version :10

• Sequence 1: NP_000124.1
• Gene: F9 / 2158
• HGNCID: 3551
• Length: 461
• Species: Homo sapiens
• Sequence 2: NP_648707.2
• Gene: CG4613 / 39586
• FlyBaseID: FBgn0036427
• Length: 374
• Species: Drosophila melanogaster
• Alignment Length: 287
• Identity: 96/287 - (33%)
• Similarity: 147/287 - (51%)
• Gaps: 23/287 - (8%)

Human   182 SVSQTSKLTRAETVFPDVDYVNSTEAETI-LDNITQSTQSFNDFTRVVGGEDAKPGQFPWQVVLN 245
            |:..||..:.|..|||    :....|:.. ::.....|....:..|:|||...:..::||...:.
  Fly    95 SLGSTSLSSSASPVFP----LEGGGAKAFRVNRCASCTCGVPNVNRIVGGTQVRTNKYPWIAQII 155

Human   246 GKVDAFCGGSIVNEKWIVTAAHCVE----TGVKITVVAGEHNIEETEHTEQKRNVIRIIPHHNYN 306
            .....||||:::|:::::||||||.    .||.:.::..:.:   :.|....|:|.....|..|:
  Fly   156 RGTFLFCGGTLINDRYVLTAAHCVHGMDMRGVSVRLLQLDRS---STHLGVTRSVAFAHAHVGYD 217

Human   307 AAINKYNHDIALLELDEPLVLNSYVTPICIADKEYTNIFLKFGSGYVSGWGRVFHKGRSALVLQY 371
            ..  ...||||||.||:|:.|...:.|.|:......|  ..|....|:|||.....|.::.|||.
  Fly   218 PV--SLVHDIALLRLDQPIPLVDTMRPACLPSNWLQN--FDFQKAIVAGWGLSQEGGSTSSVLQE 278

Human   372 LRVPLVDRATCLRSTKF--TIYNNMFCAGF-HEGGRDSCQGDSGGPHVTEVEGTSF-LTGIISWG 432
            :.||::..|.| |:|.:  .|.:.|.|||: ..||||:||||||||.:  |....| |.|::|:|
  Fly   279 VVVPIITNAQC-RATSYRSMIVDTMMCAGYVKTGGRDACQGDSGGPLI--VRDRIFRLAGVVSFG 340

Human   433 EECAMKGKYGIYTKVSRYVNWIKEKTK 459
            ..||.....|:||:||||:.||...|:
  Fly   341 YGCAKPDAPGVYTRVSRYLEWIAVNTR 367

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
F9	NP_000124.1	GLA	28..92	CDD:214503
		EGF_CA	93..129	CDD:238011
		FXa_inhibition	134..170	CDD:464251
		Tryp_SPc	227..457	CDD:238113	85/237 (36%)
CG4613	NP_648707.2	Tryp_SPc	136..362	CDD:214473	84/235 (36%)