Protein Alignment F9 and CG18420

DIOPT Version :10

• Sequence 1: NP_000124.1
• Gene: F9 / 2158
• HGNCID: 3551
• Length: 461
• Species: Homo sapiens
• Sequence 2: NP_995715.1
• Gene: CG18420 / 2768924
• FlyBaseID: FBgn0028866
• Length: 299
• Species: Drosophila melanogaster
• Alignment Length: 272
• Identity: 75/272 - (27%)
• Similarity: 120/272 - (44%)
• Gaps: 32/272 - (11%)

Human   194 TVFPDVDYVNSTEAETILDNITQSTQSFNDFTRVVGGEDAKPGQFPWQVVLNGKVDAF-CGGSIV 257
            ||||   .:.||:   .||:...:........|:|.|:.|.....||...|:...:.| |||:::
  Fly    16 TVFP---LLGSTQ---FLDSECGTRSPLKLGPRIVNGKVAVRNSSPWMAFLHTSSNQFICGGTLI 74

Human   258 NEKWIVTAAHCVETGVKITVVAGEHNIEETEHTEQKRNVIRIIPHHNYNAAINKYNHDIALLELD 322
            :.:.::|||||......|.|..||:| .:.:...::..|.|...|..|:.  |.:.:|||||.|.
  Fly    75 SRRLVLTAAHCFIPNTTIVVRLGEYN-RKLKGYREEHQVNRTFQHRFYDP--NTHANDIALLRLV 136

Human   323 EPLVLNSYVTPICI---ADKEYTNIFLKFGSGYVSGWGRV--FHKGRSALVLQYLRVPLVDRATC 382
            ..:|..:.:.||||   |..::....:|..:|  :||||.  .|.......|...|.|   ...|
  Fly   137 SNVVYKANIRPICIMWDASWKHHIDSIKVLTG--TGWGRTESMHDSSELRTLDISRQP---SKMC 196

Human   383 LRSTKFTIYNNMFCAGFHEGGRDSCQGDSGGPHVTEVEGTSFL----TGIISWGEECAMKGKYGI 443
            ...   ::.:|.||||  ....:.|.||:|||....|...:..    .||....:.|.   :..:
  Fly   197 AFG---SVLSNQFCAG--NWNSNLCIGDTGGPVGAMVRYRNAFRFVQVGIAITNKRCQ---RPSV 253

Human   444 YTKVSRYVNWIK 455
            :|.|..::.:|:
  Fly   254 FTDVMSHIEFIR 265

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
F9	NP_000124.1	GLA	28..92	CDD:214503
		EGF_CA	93..129	CDD:238011
		FXa_inhibition	134..170	CDD:464251
		Tryp_SPc	227..457	CDD:238113	66/239 (28%)
CG18420	NP_995715.1	Tryp_SPc	42..264	CDD:214473	66/237 (28%)